MIAMI, USA: People who are genetically predisposed to storing belly fat, or having an apple-shaped body type, could face a higher risk of type 2 diabetes and heart disease, researchers said Tuesday.
The study in the Journal of the American Medical Association (JAMA) suggests a person’s genetic makeup may cause health problems down the road.
“People vary in their distribution of body fat — some put fat in their belly, which we call abdominal adiposity, and some in their hips and thighs,” said senior author Sekar Kathiresan, associate professor of Medicine at Harvard Medical School.
“We tested whether genetic predisposition to abdominal adiposity was associated with the risk for type 2 diabetes and coronary heart disease and found that the answer was a firm ‘yes’.”
Previous observational studies have uncovered a link between belly fat and type 2 diabetes and heart disease, but fell short of proving cause and effect.
To investigate further, researchers examined six studies conducted from 2007 to 2015, including some 400,000 participants whose genomes were analyzed.
Previous research had identified 48 gene variants associated with waist-to-hip ratio, resulting in a genetic risk score.
They found that people with certain genes that predisposed them to higher waist-to-hip ratio also had higher lipids, insulin, glucose and systolic blood pressure, as well as a higher risk for type 2 diabetes and heart disease.
“These results illustrate the power of using genetics as a method of determining the effects of a characteristic like abdominal adiposity on cardiometabolic outcomes,” said lead author Connor Emdin, a researcher at Massachusetts General Hospital.
Since researchers did not find any links between body type, genetic risk score and confounding factors such as diet and smoking, that “provides strong evidence that abdominal adiposity itself contributes to causing type 2 diabetes and heart disease,” he added.
Emdin said the findings could one day lead to the development of drugs designed to target belly fat, and perhaps lower the risk of diabetes and heart disease.
'Apple-shaped' body could raise risk of diabetes
'Apple-shaped' body could raise risk of diabetes
Where We Are Going Today: ‘Phet Phet’ Thai restaurant in Riyadh
Located at Pure Center on Takhassusi Road, Phet Phet is one of the boldest Thai kitchens to hit Riyadh — and it lives up to its name, which literally means “very spicy.”
With its neon signs, playful branding, and sleek modern seating, the place feels like a Bangkok street stall reimagined with modern aesthetics.
The menu leans heavily into bold, unapologetic flavors. I started with the shrimp cashew for SR75 ($20) — a standout dish that combined sweet, savory, and spicy notes perfectly, with just the right crunch.
Another favorite was the tom yum nam khon for SR 55, a rich and creamy soup layered with lemongrass, lime, and plump shrimp. It was intense and comforting at the same time.
Among the many appetizers we tried, the pow pow shrimp, chili wontons, and prawn toast all delivered.
The pad ki mao chicken and panang curry chicken were flavorful, with deep spice profiles that felt authentic. Even side dishes like sticky rice, coconut rice, and the playful Kinza cola added to the experience.
For dessert, the mango sticky rice (SR 35) offered a cool, sweet end to the fiery meal.
The place runs on energy — fast service, loud tables, and constant movement from the open kitchen to the packed dining area.
But here’s the only downside: Phet Phet is small. With how popular it already is, the space can feel cramped, and getting a seat without a wait is tricky.
Still, for those who love real heat, bold flavors, and a vibe that feels straight out of Thailand, Phet Phet is a must-visit.
For more information, check their Instagram @phetphetsa.
Where We Are Going Today: ‘Noria Furn’ bakery in Riyadh
- Noria Furn is a charming bakery with an early closing time that makes it ideal only for those who rise with the sun
Nestled in the lively Rayyan district of eastern Riyadh, Noria Furn is bakery that specializes in Middle Eastern breakfast staples.
Open from 6 a.m. to 1:30 p.m., it is an ideal spot for early birds eager to indulge in freshly baked goods, such as pies, mankoosha, falafel, and more.
The smell of freshly baked bread sets the tone as you enter, offering an appetizing and warm welcome.
On recent visits, I was impressed by the attentive and welcoming service, even when the outlet was bustling with customers.
Each dish I tried, from the taghmeesat shakshouka to the akawi cheese, was fresh, flavorful, and artfully presented. The cozy atmosphere, enhanced by the absence of background music, creates an inviting space for a leisurely meal.
However, there are areas for improvement. Prices are on the high side, which might not suit every budget, even if the quality largely justifies the cost.
I noticed their hot drinks, such as karak and tea, did not stay warm long enough. Using kettles with a base to maintain temperature could greatly enhance the overall experience.
While the tandoor bread was delightful, offering a wheat option would accommodate a wider range of dietary preferences.
Noria Furn is a charming bakery with an early closing time that makes it ideal only for those who rise with the sun. I look forward to returning and seeing how they continue to develop their offerings.
Where We Are Going Today: ‘Sign’ burgers in Riyadh
- One of the highlights was the Sign box, which includes four burgers and four fries, ideal for gatherings
If you’re in Riyadh and looking for a burger spot that delivers on both taste and value, Sign should be on your list.
With eye-catching pink branding and loyal customers, it is clear they have tapped into a winning formula: simple, good food done right.
I tried their classic burger meal, which includes fries and a drink, and was genuinely surprised to get all that flavor for just SR24 ($6.40). The patty was juicy, the bun soft, and the sauce had the perfect tang without overpowering the rest of the ingredients. It felt well-balanced and satisfying, not greasy or heavy.
One of the highlights was the Sign box, which includes four burgers and four fries, ideal for gatherings. Sign uses locally sourced ingredients from Saudi farms, which is also a major plus — you can taste the difference in the quality of the meat and vegetables.
Whether you’re grabbing a quick bite through their drive-thru or sitting down with friends, it’s a spot that gets it right without overcomplicating things.
If there is one downside, it is the wait. The place is almost always packed — a sign (no pun intended) of how popular it has become. But if you are happy to queue, it is absolutely worth checking out.
For more, check their Instagram @signsa_
Where We Are Going Today: ‘Avindar Lounge’ in Riyadh
- The lights are dimmed every Tuesday night for a candlelit experience with a pianist playing live music, creating an atmospheric experience for guests
With four locations across the Kingdom’s capital, Avindar Lounge offers a space where you can enjoy lush greenery and good food.
The lounge I visited is located on the northeast side of Riyadh and includes a separate section for smokers.
The menu is diverse and appeals to different tastes, so you can sample anything from Middle Eastern kebabs to pasta and burgers.
The lights are dimmed every Tuesday night for a candlelit experience with a pianist playing live music, creating an atmospheric experience for guests.
I tried the mixed appetizer, which was flavorful and memorable. It included hummus, tabouli, dolma, and baba ghanoush.
And while I am generally not a fan of sweet beverages, I genuinely enjoyed their hot chocolate, which was not overwhelmingly sweet or creamy.
However, considering the portion sizes, which are enough for one person, customers might find the prices a bit high.
But the music and bird sounds, paired with the lounge’s colorful and cozy interior, make Avindar a refreshing spot for dining or coffee with friends.
Where We Are Going Today: ‘Dakkat Haretna’ restaurant in Riyadh
Located in the bustling Al-Munsiyah neighborhood of Riyadh, Dakkat Haretna is a charming eatery that captures the essence of Saudi Arabia cuisine.
The interior is adorned with Qatt Asiri art, traditional Saudi motifs that resonate with the spirit of the region. The windows, designed in the Hijazi roshan style, add to the charming appeal of the space which is cozy and family friendly.
Behind the menu is chef Douha Al-Otaishan, whose vision brings to life dishes that celebrate the rich culinary heritage of Saudi Arabia.
I sampled the beetroot salad, which had refreshing ingredients, complemented by feta cheese balls and crisp lettuce, that set the stage for the main course.
The marqooq beef and “happiness kabsa,” Al-Otaishan’s signature dish, were both memorable. I polished off the flavorful marqooq in no time.
The kabsa, with its tender chicken, was delightful despite the rice being a tad drier than what I usually enjoy. The accompanying tangy red sauce elevated the dish by adding a burst of flavor.
Other notable options for those wishing to explore Saudi cuisine are jareesh, qursan, and kubaiba Hail.
Their breakfast menu is equally enticing, providing classics including tamees, foul, and shakshooka, available from 7 a.m.
If you enjoy cooking and want to recreate Saudi dishes at home, the restaurant also offers the chef’s blends of spices.
With attentive service, fair prices, and a calm ambiance free of noisy music, Dakkat Haretna is a comfortable place to enjoy traditional dishes or try something new.
Whether you are familiar with Saudi cuisine or just curious, it is a spot worth visiting.
