DUBAI: Israel unleashed airstrikes across Iran for a third day on Sunday and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country.]

Planned talks on Iran's nuclear program, which could provide an off-ramp, were canceled. The sixth round of US-Iran indirect talks on Sunday over Iran ‘s nuclear program will not take place, mediator Oman said.

The region braced for a protracted conflict after Israel's surprise bombardment of Iran's nuclear and military sites on Friday killed several top generals and nuclear scientists, and neither side showed any sign of backing down. Iran said Israel struck two oil refineries, raising the prospect of a broader assault on Iran's heavily sanctioned energy industry that could affect global markets.

The Israeli military, in a social media post, warned Iranians to evacuate arms factories, signaling what could be a further widening of the campaign. Around noon local time, explosions were heard again in the Iranian capital, Tehran.

US President Donald Trump has expressed full support for Israel’s actions while warning Iran that it can only avoid further destruction by agreeing to a new nuclear deal.

Iranian Foreign Minister Abbas Araghchi said Sunday that if the Israeli strikes on Iran stop, then “our responses will also stop.” He said the United States “is a partner in these attacks and must take responsibility.”

Explosions in Tehran

New explosions echoed across Tehran and were reported elsewhere in the country early Sunday, but there was no update to a death toll released the day before by Iran’s UN ambassador, who said 78 people had been killed and more than 320 wounded.

In Israel, at least 10 people were killed in Iranian strikes overnight and into Sunday, according to Israel’s Magen David Adom rescue service, bringing the country’s total death toll to 13. The country’s main international airport and airspace remained closed for a third day.

Israeli strikes targeted Iran’s Defense Ministry early Sunday after hitting air defenses, military bases and sites associated with its nuclear program. The killing of several top generals and nuclear scientists in targeted strikes indicated that Israeli intelligence has penetrated Iran at the highest levels.

Death toll mounts in Israel

In Israel, at least six people, including a 10-year-old and a 9-year-old, were killed when a missile hit an apartment building in Bat Yam, near Tel Aviv. Daniel Hadad, a local police commander, said 180 people were wounded and seven are still missing.

An Associated Press reporter saw streets lined with damaged and destroyed buildings, bombed out cars and shards of glass. Responders used a drone at points to look for survivors. Some people could be seen leaving the area with suitcases.

Another four people, including a 13-year-old, were killed and 24 wounded when a missile struck a building in the Arab town of Tamra in northern Israel. A strike on the central city of Rehovot wounded 42.

The Weizmann Institute of Science, an important center for research in Rehovot, said “there were a number of hits to buildings on the campus.” It said no one was harmed.

Israel has sophisticated multi-tiered air defenses that are able to detect and intercept missiles fired at populated areas or key infrastructure, but officials acknowledge it is imperfect.

Israel attacks defense ministry facility in Isfahan

Iranian media said Sunday that Israel attacked a facility affiliated with the defense ministry in the central city of Isfahan, on the third consecutive day of Israeli strikes.

“One of the centers affiliated with the Ministry of Defense in Isfahan was attacked, and possible damages are under investigation,” ISNA news agency reported quoting deputy provincial governor Akbar Salehi.

Pipelines, transmission lines in Haifa damaged

Israel’s Oil Refineries said its pipelines and transmission lines in Haifa had been damaged by missile strikes by Iran, according to a regulatory filing to the Tel Aviv Stock Exchange.

It said that no injuries or casualties were reported at the sites, with refining facilities continuing to operate despite a shutdown of some downstream operations.

It said it is examining the impact of the damage on its operations and implications on its financial results.

Israeli military issues evacuation warning to Iranians

Israel on Sunday issued an evacuation warning to Iranians residing near weapons facilities in Iran, an Israeli military spokesperson said in a post on X in Arabic and Farsi.

The spokesperson said the evacuation warning includes all weapons factories and supporting facilities.

Iran FM says has ‘solid proof’ US forces supported Israel in attacks

Araghchi said Sunday Tehran had evidence to show US forces supported the intense bombardment campaign Israel launched against the Islamis republic this week.

“We have solid proof of the support of the American forces and American bases in the region for the attacks of the Zionist regime military forces,” Araghchi told foreign diplomats in a meeting broadcast on state TV.

Araghchi also slammed the United Nations Security Council, accusing it of “indifference” over Israel’s deadly attacks on the Islamic republic.

Gas field attack

In the first apparent attack to hit Iran’s energy infrastructure, Tasnim news agency said Iran partially suspended production at South Pars, the world’s biggest gas field, after an Israeli strike caused a fire there on Saturday.

The South Pars field, offshore in Iran’s southern Bushehr province, is the source of most of the gas produced in Iran.

Fears about potential disruption to the region’s oil exports had already driven up oil prices 9 percent on Friday even though Israel spared Iran’s oil and gas on the first day of its attacks.

An Iranian general, Esmail Kosari, said on Saturday that Tehran was reviewing whether to close the Strait of Hormuz controlling access to the Gulf for tankers.

With Israel saying its operation could last weeks, and Netanyahu urging Iran’s people to rise up against their Islamic clerical rulers, fears have grown of a regional conflagration dragging in outside powers.

B’Tselem, a leading Israeli human rights organization, said on Saturday that instead of exhausting all possibilities for a diplomatic resolution, Israel’s government had chosen to start a war that puts the entire region in danger.

Tehran has warned Israel’s allies that their military bases in the region would come under fire too if they helped shoot down Iranian missiles.

However, 20 months of war in Gaza and a conflict in Lebanon last year have decimated Tehran’s strongest regional proxies, Hamas in Gaza and Hezbollah in Lebanon, reducing its options for retaliation.

Israel sees Iran’s nuclear program as a threat to its existence, and said the bombardment was designed to avert the last steps to production of a nuclear weapon.

Tehran insists the program is entirely civilian and that it does not seek an atomic bomb. The UN nuclear watchdog, however, reported Iran this week as violating obligations under the global non-proliferation treaty.

Iran says scores killed

Iran said 78 people were killed on the first day of Israel’s campaign, and scores more on the second, including 60 when a missile brought down a 14-story apartment block in Tehran, where 29 of the dead were children.

Iran had launched its own retaliatory missile volley on Friday night, killing at least three people in Israel.

With Israel saying its operation could last weeks, and Netanyahu urging Iran’s people to rise up against their Islamic clerical rulers, fears have grown of a regional conflagration dragging in outside powers.

‘We will hit every site’

Israel said three people were killed and 76 wounded by Iran’s retaliatory drone and missile barrage overnight, which lit up the skies over Jerusalem and Tel Aviv.

Israeli Prime Minister Benjamin Netanyahu vowed to keep up Israel’s campaign.

“We will hit every site, every target of the ayatollah regime,” he said in a video statement, threatening greater action “in the coming days.”

He added that the Israeli campaign had dealt a “real blow” to Iran’s nuclear program and maintained it had the “clear support” of US President Donald Trump.

Netanyahu’s defense minister, Israel Katz, warned “Tehran will burn” if it kept targeting Israeli civilians.

Urgent calls to deescalate

World leaders made urgent calls to deescalate and avoid all-out war. The attack on nuclear sites set a “dangerous precedent,” China’s foreign minister said.

The region is already on edge as Israel makes a new push to eliminate the Iranian-backed militant group Hamas in Gaza after 20 months of fighting.

After decades of enmity and conflict by proxy, it is the first time the arch-enemies have traded fire with such intensity, triggering fears of a prolonged conflict that could engulf the Middle East.

Highlighting the unease, Turkish President Recep Tayyip Erdogan warned against a “devastating war” with regional consequences in a call with Saudi Crown Prince Mohammed bin Salman, Ankara said.

Jordan reopens airspace

Jordan announced the reopening of its airspace Sunday morning after a night of attacks by arch-foes Israel and Iran.

The civil aviation authority in Jordan, which borders Israel, said in a statement that the country’s airspace had been reopened “for civilian flights following a careful risk assessment.”

Turkiye denies sharing information with Israel

At the United Nations, the Turkish mission dismissed as "black propaganda" reports that “information was shared with Israel from the radar base in Kürecik.”

In a statement, the mission said the Kürecik Radar Station, a NATO installation, was established in line with Türkiye's national security and interests and is intended to ensure the protection of the NATO allies.

"The data obtained from the Kürecik radar base is exclusively shared with NATO allies within a specific framework, in accordance with NATO procedures," said the statement. "Sharing radar base data with non-NATO allies, such as Israel, is absolutely out of the question."

It maintained that "Türkiye stands against Israel's operations to destabilize the Middle East and will never support Israel's actions in this regard."

Reports of alleged data transmission came a day after Israel, without any provocation, bombarded Iran's capital on Friday. 

Iran calls nuclear talks ‘unjustifiable’

“We remain committed to talks and hope the Iranians will come to the table soon,” said a senior US official, speaking on condition of anonymity to discuss diplomacy.

Iran says its nuclear program is for peaceful purposes only, and US intelligence agencies have assessed that Tehran was not actively pursuing the bomb. But its uranium enrichment has reached near weapons-grade levels, and on Thursday, the UN’s atomic watchdog censured Iran for not complying with obligations meant to prevent it from developing a nuclear weapon.

Iran’s top diplomat said Saturday the nuclear talks were “unjustifiable” after Israel’s strikes. Abbas Araghchi’s comments came during a call with Kaja Kallas, the European Union’s top diplomat.

The Israeli airstrikes were the “result of the direct support by Washington,” Araghchi said in a statement carried by the state-run IRNA news agency. The US has said it isn’t part of the strikes.

On Friday, US President Donald Trump urged Iran to reach a deal with the US on its nuclear program, adding that “Iran must make a deal, before there is nothing left.”

‘More than a few weeks’ to repair nuclear facilities

Israel attacked Iran’s main nuclear enrichment facility in Natanz. Satellite photos analyzed by AP show extensive damage there. The images shot Saturday by Planet Labs PBC show multiple buildings damaged or destroyed. The structures hit include buildings identified by experts as supplying power to the facility.

UN nuclear chief Rafael Grossi told the Security Council that the above-ground section of the Natanz facility was destroyed. The main centrifuge facility underground did not appear to have been hit, but the loss of power could have damaged infrastructure there, he said.

Israel said it also struck a nuclear research facility in Isfahan, including “infrastructure for enriched uranium conversion,” and said it destroyed dozens of radar installations and surface-to-air missile launchers in western Iran. Iran confirmed the strike at Isfahan.

The International Atomic Energy Agency said four “critical buildings” at the Isfahan site were damaged, including its uranium conversion facility. “As in Natanz, no increase in off-site radiation expected,” it added.

An Israeli military official, speaking on condition of anonymity in line with official procedures, said that according to the army’s initial assessment “it will take much more than a few weeks” for Iran to repair the damage to the Natanz and Isfahan nuclear sites. The official said the army had “concrete intelligence that production in Isfahan was for military purposes.”

Israel denied it had struck the nuclear enrichment facility in Fordo, about 100 kilometers (60 miles) southeast of Tehran.

Among those killed were three of Iran’s top military leaders: one who oversaw the entire armed forces, Gen. Mohammad Bagheri; one who led the paramilitary Revolutionary Guard, Gen. Hossein Salami; and the head of the Guard’s aerospace division, which oversees its arsenal of ballistic missile program, Gen. Amir Ali Hajjizadeh. On Saturday, Khamenei named a new leader for the Revolutionary Guard’s aerospace division: Gen. Majid Mousavi.

Iran rallies citizens to unite, ‘rise up’ says Netanyahu

Iran called on its citizens to unite in the country’s defense, while Netanyahu urged them to rise up against against the government.

Iran’s Mehr news agency said Tehran had warned Britain, France and the United States it could retaliate if they came to Israel’s defense.

AFP images from the city of Ramat Gan near Tel Aviv showed blown-out buildings, destroyed vehicles and streets strewn with debris after Iran’s first wave of attacks.

Iran’s Revolutionary Guards said they had struck dozens of targets in Israel. One Iranian missile wounded seven Israeli soldiers, the military said.

Firefighters had worked for hours to free people trapped in a Tel Aviv high-rise building on Friday.

Chen Gabizon, a resident, said he ran to an underground shelter after receiving an alert.

“We just heard a very big explosion, everything was shaking, smoke, dust, everything was all over the place,” he said.

In Tehran, fire and heavy smoke billowed over Mehrabad airport on Saturday, an AFP journalist said.

The Israeli army said it had struck an underground military facility Saturday in western Iran’s Khorramabad that contained surface-to-surface and cruise missiles.

Iranian media also reported a “massive explosion” following an Israeli drone strike on an oil refinery in the southern city of Kangan.

The attacks prompted several countries to temporarily ground air traffic, though on Saturday Jordan, Lebanon and Syria reopened their airspace.

Iran’s airspace was closed until further notice, state media reported, as was Israel’s, according to authorities.