Genetic clues hint at hidden virus cases in Washington state

Medics prepare to transfer a patient on a stretcher to an ambulance at the Life Care Center of Kirkland, the long-term care facility linked to the two of three confirmed coronavirus cases in the state, in Kirkland, Washington, on March 1, 2020. (REUTERS/David Ryder)
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Updated 02 March 2020
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Genetic clues hint at hidden virus cases in Washington state

  • Health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus
  • The first US case was a Washington state man who had visited China, where the virus first emerged

SEATTLE: The coronavirus may have been circulating for weeks undetected in Washington state, a preliminary finding that could mean hundreds of undiagnosed cases, researchers said Sunday after analyzing the genetic sequences of viruses from two people.
Washington state, home of the nation’s first confirmed infection, has seen eight confirmed cases, including the nation’s first death from the virus this weekend.
State and local authorities stepped up testing for the illness as the number of new cases grew nationwide, with new infections announced in California, Illinois, Rhode Island, New York and Washington state. Authorities in the Seattle area said two more people had been diagnosed with the COVID-19 virus, both men in their 60s who were in critical condition, and two health care workers in California were also diagnosed.
A man in his 50s died in Washington on Saturday, and health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus. The first US case was a Washington state man who had visited China, where the virus first emerged, but several recent cases in the US have had no known connection to travelers.
In California, two health care workers in the San Francisco Bay area who cared for an earlier coronavirus patient were diagnosed with the virus on Sunday, the Alameda and Solano counties said in a joint statement.
The health care workers are both employed at NorthBay VacaValley Hospital in Vacaville, California, and had exposure to a patient treated there before being transferred to UC Davis Medical Center in Sacramento, the statement said. That patient was the first person in the US discovered to have contracted the coronavirus with no known overseas travel.
Alameda County declared a state of emergency on Sunday following the news.
Elsewhere, authorities announced Sunday a third case in Illinois and Rhode Island and New York’s first cases as worried Americans swarmed stores to stock up on basic goods such as bottled water, canned foods and toilet paper.
The hospitalized patient in Rhode Island is a man in his 40s who had traveled to Italy in February. New York confirmed Sunday that a woman in her late 30s contracted the virus while traveling in Iran. The patient is not in serious condition. She has respiratory symptoms and has been in a controlled situation since arriving in New York, according to a statement from the governor’s office.
As the fallout continued, Vice President Mike Pence and Health and Human Services Secretary Alex Azar sought to reassure the American public that the federal government is working to make sure state and local authorities are able to test for the virus. Both said during a round of TV talk show appearances Sunday that thousands more testing kits had been distributed to state and local officials, with thousands more to come.
“They should know we have the best public health system in the world looking out for them,” Azar said, adding that additional cases will be reported and the overall risk to Americans is low.
As the cases ticked up, some Americans stocked up on basic supplies — particularly in areas with diagnosed cases — and began to take note of the impact on daily life. Stores such as Costco sold out of toilet paper, bottled water and hand sanitizer outside Portland, Oregon, where a case was announced Friday. Sports games and practices were canceled into the coming school week. Some churches said they would not offer communion because of fears of viral spread.
As Americans prepared, researchers at the Fred Hutchinson Cancer Research Center and the University of Washington on Sunday said they had evidence the virus may have been circulating in the state for up to six weeks undetected — a finding that, if true, could mean hundreds of undiagnosed cases in the area. They posted their research online, but it was not published in a scientific journal or reviewed by other scientists.
Trevor Bedford, an associate professor who announced the preliminary findings on the virus in Washington state, said on Twitter late Saturday that genetic similarities between the state’s first case on Jan. 20 and a case announced Friday indicated the newer case may have descended from the earlier one. The Jan. 20 case was the first known case in the US
“I believe we’re facing an already substantial outbreak in Washington State that was not detected until now due to narrow case definition requiring direct travel to China,” he said on Twitter.
Bedford did not immediately reply to an email requesting an interview Sunday.
Scientists not affiliated with the research said the results did not necessarily surprise them and pointed out that for many people — especially younger, healthier ones — the symptoms are not much worse than a flu or bad cold.
“We think that this has a pretty high rate of mild symptoms and can be asymptomatic. The symptoms are pretty non-specific and testing criteria has been pretty strict, so those combinations of factors means that it easily could have been circulating for a bit without us knowing,” said Justin Lessler, an associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.
Dr. Adam Lauring of University of Michigan called the findings “high quality work” from scientists who’ve done similar work with the flu virus for years.
“They show their data and they show their work,” Lauring said. “It’s more than a series of tweets” because the researchers back up what they found with data that they’ve shared online. “If there’s something wrong, someone will find it.”
Dr. Carlos del Rio of Emory University School of Medicine said the findings are from respected researchers in genomic sequencing and they make sense because of the geographic proximity of the two cases.
“This is a good time to reinforce the things we all should be doing to stop the spread of flu. Wash your hands. Don’t touch your face. If you have a cold, stay home ... It’s a good time to remind ourselves of that,” he said.
Pence, named by the president to be the point-person overseeing the government’s response, said more than 15,000 virus testing kits had been released over the weekend. And, the administration is working with a commercial provider to distribute 50,000 more, he said.
The vice president said testing was among the first issues raised by governors he’s spoken with so far. Several states have begun their own testing, including Washington state, Oregon and Illinois.
“We’re leaning into it,” Pence said.
Azar said more than 3,600 people already have been tested for coronavirus and the capability exists to test 75,000 people. He forecast a “radical expansion of that” in the coming weeks.
Pence and Azar spoke a day after President Donald Trump approved new restrictions on international travel to prevent the spread within the US of the new virus, which originated in China. There are now more than 80,000 cases worldwide and about 3,000 deaths.
Two Americans are now known to have died of the virus, one in Washington state and one in China.
The new US travel restrictions apply to Iran, although travel there by Americans already is severely limited, as well as heavily affected regions of Italy and South Korea. Trump tweeted Sunday that any travelers from those countries will be screened when they arrive in the US
The number of known coronavirus cases in the US had reached76 as of Sunday, counting people evacuated from a cruise ship and the city of Wuhan in China.
Trump said Saturday at a White House news conference that he was thinking about closing the southern border with Mexico as a precaution. Azar said Sunday that Mexico has few coronavirus cases and that it would take a dramatic change in the circumstances there to prompt serious consideration of a border shutdown.
The president, Azar said, “was trying to say everything’s on the table.”
“We will take whatever measures are appropriate and necessary to protect the American people, but we don’t forecast doing that any time soon,” he said of closing the border.
Pence noted that an infectious disease expert is joining an existing White House coronavirus task force on Monday. Last week, Pence announced the addition of Debbie Birx, a State Department ambassador-at-large and medical doctor who is the administration’s global HIV/AIDS response coordinator, to the virus panel.
Despite calls by Trump and Pence for political unity in the face of the viral threat, the issue has become mired in the partisan rancor in Washington, with both Republicans and Democrats accusing each other of mining the issue for political gain.
Trump, at a political rally last week, accused Democrats of “politicizing” the issue and said their criticism of his handling of the public health challenge was their new “hoax.”
At the White House on Saturday, Trump said he was not trying to minimize the threat from the virus.
“Again, the hoax was used in respect to Democrats and what they were saying,” he said Saturday.
Democratic presidential candidate Joe Biden, who emerged victorious Saturday night from South Carolina’s primary, criticized the administration over the availability of testing kits.
Biden also panned the administration’s decision to have political appointees Pence and Azar, neither of whom are scientists by training, appear on the Sunday shows, instead of an expert like Dr. Anthony Fauci, the National Institutes of Health infectious disease chief.
Biden claimed the administration doesn’t have testing kits. Pence and Azar said thousands of kits had been distributed.
Azar said he didn’t know what Biden was talking about when the former vice president said testing kits didn’t exist. Azar said the Centers for Disease Control and Prevention had developed a lab test for coronavirus with “historic speed.”
Pence was interviewed on CNN’s “State of the Union” and Azar commented on “Fox News Sunday,” CBS’ “Face the Nation” and ABC’s “This Week.” Biden commented on CNN.


Explosions kill 1 man outside Brazil’s Supreme Court and force justices to evacuate

Updated 56 min 16 sec ago
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Explosions kill 1 man outside Brazil’s Supreme Court and force justices to evacuate

  • Local media reported that the blasts took place with 20 seconds between the first and the second explosions

SAO PAULO: Two explosions outside Brazil’s Supreme Court on Wednesday killed a man and forced the justices and staff to evacuate the building in the capital of Brasilia.
The court said in a statement that two very strong blasts were heard at about 7:30 p.m. local time, shortly after Wednesday’s session finished. It added that all the justices and staff left the building safely after the incident.
Local firefighters confirmed that one man died at the scene, but did not identify him.
Celina Leão, the lieutenant governor of Brazil’s federal district, recommended that Congress be closed on Thursday to avoid new risks. She said police believe the man who died caused the explosions.
“It could have been a lone wolf, like others we’ve seen around the world,” Leão said in a news conference. “We are considering it as a suicide because there was only one victim. But investigations will show if that was indeed the case.”
Leão added only forensics will be able to identify the body, which remained outside the Supreme Court for two hours after the incident.
Local media reported that the blasts took place with 20 seconds between the first and the second explosions.
The incident took place in Brasilia’s Three Powers Plaza, an area where Brazil’s main government buildings, including the Supreme Court, Congress and presidential palace, are located.
President Luiz Inácio Lula da Silva was not in the neighboring presidential palace at the time of the blasts, said spokesman José Chrispiniano.
Police blocked all access to the area and the presidential security bureau was conducting a sweep of the grounds around the presidential palace.
Brazil’s federal police said it is investigating and did not provide a motive.
The Supreme Court in recent years has become a target for threats by far-right groups and supporters of former President Jair Bolsonaro due to its crackdown on the spread of false information. In particular, Justice Alexandre de Moraes has been a focus for their ire.
Lula’s spokesman said the leftist leader is in a meeting at the presidential residence with federal police chief Andrei Rodrigues, and Supreme Court Justices de Moraes and Cristiano Zanin.
Earlier, another explosion was heard in the parking lot of Brazil’s Congress. Police said the blast apparently came out of a car, but no one was injured. Leão said authorities have already identified who is the owner of the car, but added the two incidents can only be linked after the investigations.


A diminished Biden heads to APEC summit in Peru, overshadowed by China’s Xi

Updated 14 November 2024
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A diminished Biden heads to APEC summit in Peru, overshadowed by China’s Xi

  • With the US seemingly headed back toward isolationism under Trump, “China will be seen as the alternative,” says analyst
  • President Xi’s first order of business in Peru is inaugurating a $1.3 billion megaport that will put China’s regional influence on stark display

LIMA, Peru: If things had gone differently last week, US President Joe Biden could have arrived at the Asia-Pacific Economic Cooperation forum in Peru on Thursday projecting confidence and pledging his successor’s cooperation with eager Latin American partners. No longer.
Just as in 2016, the last time that Peru’s capital Lima hosted APEC, Donald Trump’s election victory has pulled the rug out from under a lame-duck Democrat at the high-profile summit attended by over a dozen world leaders.
The renewed prospect of Trump’s “America First” doctrine hampers Biden’s ability to reinforce the United States’ profile on his first presidential trip to South America, experts say, leaving China and its leader, Xi Jinping, to grab the limelight in America’s proverbial backyard.
President Xi’s first order of business in Peru is inaugurating a $1.3 billion megaport that will put China’s regional influence on stark display. Total investment is expected to top $3.5 billion over the next decade.
“This isn’t the way the US had hoped to participate in the summit,” said Margaret Myers, the director of the China and Latin America program at the Inter-American Dialogue, a Washington policy group. “All eyes are going to be on the port, what Xi says about it and how he articulates relations across the Pacific.”
With the US seemingly headed back toward isolationism under Trump, “China will be seen as the alternative,” Myers added.
Sitting 60 kilometers (37 miles) northeast of Lima, the Chancay megaport — once a serene fishing village — is perhaps the clearest sign of Latin America’s reorientation. The Chinese shipping and logistics giant Cosco holds a 60 percent stake in the project it developed with Peruvian partner, Volcan.
“With this port, we’re looking at the entire Pacific coast, from the United States and Canada all the way to Chile,” Peruvian Foreign Minister Elmer Schialer told The Associated Press in his office on Monday. “The shipping business is being transformed.”
Peruvian Economy Minister José Arista said in June during a visit to China that the country’s neighbors — Brazil, Colombia, Chile — are “making constant trips to and from to see how they can modify their supply chain to use this port,” which will cut shipping time to Beijing by 10 days.
China’s trade with the region ballooned 35-fold from 2000 to 2022, reaching nearly $500 billion, according to data from the Economic Commission for Latin America and the Caribbean. Most of the region’s exports came from South America and were concentrated in five products: soybeans, copper and iron ore, oil and copper cathodes.
At the same time, China’s diplomatic engagement in the region has become more effective, with Xi visiting 11 Latin American countries since becoming president, according to Xinhua, China’s main state news agency. Brazil, host of the G20 summit, and Peru will bestow the rare honor of a full state visit to Xi this month, but not to Biden.
The misguided notion that Latin America must choose between its two largest trading partners is “a strategic defeat” for the US, said Eric Farnsworth, vice president at the Washington-based Council of the Americas.
“The idea that China is somehow a better partner is increasingly being heard around the region and I think Xi wants to solidify that and amplify that,” Farnsworth said.
Roughly a decade after China poured billions of dollars into building power plants, roads, airports and other infrastructure that saddled some developing countries with unserviceable debt, few expect Beijing to direct more massive loans to Latin America through its Belt and Road Initiative. But deeper cooperation on other infrastructure is possible, particularly renewable energy and telecommunications, said the Boston University Bulletin.
The US has appealed to Latin American governments to reject telecoms investment, particularly opposing Huawei, the Chinese tech giant that it argues could open the door to Chinese government spying. Similarly, US officials have raised concerns over the Chancay port’s possible dual-use by Beijing’s navy in the Pacific — a prospect dismissed by Chinese officials.
China “is working to exploit insecurity in our hemisphere,” said US Defense Secretary Lloyd Austin at the Southern Command headquarters in Florida this week, adding that the Asian giant is leveraging the need for investment in the Americas to advance its “malign agenda.”
Despite its objections to Chinese influence, the US hasn’t shown the ability or willingness to build infrastructure like Chancay’s megaport, experts note.
Even when the US government has worked to ensure competitive bidding in Latin American massive public works projects, American companies have refrained from participating, said Benjamin Gedan, director of the Wilson Center’s Latin America Program.
A Kamala Harris administration wouldn’t have changed that, but a Democratic victory would have enabled Biden to speak in Lima with authority about US collaboration to come, such as building regional supply chains, Gedan said.
In sharp contrast to Biden’s alliance-building approach, Trump has vowed to protect American interests and promised more of the same unilateralist action the world saw in his first term when he staked out a combative stance against foreign competitors and deepened the US trade war with China.
In 2022, Biden launched the Indo-Pacific Economic Framework to help integrate the economies of the region and enable the US to counterbalance China. But last year, on the campaign trail, Trump said he would kill the trade pact if he were to win the 2024 election and return to the White House — in the same way, he pulled the US from the Trans-Pacific Partnership immediately after taking office in 2017.
In the years since, US clout in South America has diminished while China’s has grown, said Farnsworth, recalling how the last time Lima hosted APEC in 2016, the shock of Trump’s victory sucked the energy out of then-President Barack Obama’s delegation.
Peru’s top diplomat insists that the US hasn’t ceded its dominant voice guiding discussions about trade at gatherings such as APEC — and doubted that it will, even under Trump.
“I’m not sure that Trump will go against these types of multilateral contexts just because he is worried about the American people,” Schialer said. “He knows that the US is too important for the world. We have to sit down and have a nice dialogue and see how we can face these challenges together.”
Biden will hold talks Saturday with Xi on the sidelines of APEC, according to the US president’s national security adviser, Jake Sullivan. The White House has been working for months to arrange a final meeting between Xi and Biden before the Democrat leaves office in January.
Meantime, in the wake of Trump’s win and China’s port opening in Peru, analysts expect the hard-nosed competition between the US and China to overshadow APEC.
“The Chinese love the idea of outmaneuvering the US in its near-abroad,” Gedan said. “Xi will luxuriate in this dynamic of being able to arrive with a big delegation, (...) to inaugurate this transformational port and suck all the air out of the room when his American counterpart is very weak politically. That is significant to China.”
 


Protests erupt in Paris over pro-Israel gala organized by far-right figures

Updated 14 November 2024
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Protests erupt in Paris over pro-Israel gala organized by far-right figures

  • On Wednesday night, several hundred protesters marched through central Paris, denouncing the event as a “gala of hatred and shame”

PARIS: Protests erupted in Paris on Wednesday against a controversial gala organized by far-right figures in support of Israel. The event, intended to raise funds for the Israeli military, included Israeli Finance Minister Bezalel Smotrich among its invited guests.
The demonstrations came on the eve of a high-stakes soccer match at France’s national stadium against the Israeli national team, overshadowed by tensions around the wars in the Middle East. Authorities in Paris announced that more than 4,000 police officers and 1,600 stadium staff will be deployed for the game.
Smotrich, a vocal advocate of Israeli settlements, had been expected to attend Wednesday’s gala, dubbed “Israel is Forever,” which was planned by an association of the same name. The group’s stated goal is to “mobilize French-speaking Zionist forces.”
After days of growing criticism of the event, Smotrich’s office confirmed Wednesday that the minister would not travel to Paris to participate.
But the invitation to Smotrich drew sharp criticism from local associations, unions and left-wing political parties, prompting two protests in the French capital. The minister, a hard-line settler leader, has been accused of inflaming tensions in the West Bank and drew international condemnations this week by saying he hopes the election of Donald Trump will clear the way for Israeli annexation of the West Bank — a step that would extinguish Palestinian statehood dreams.
The French Foreign Ministry called Smotrich’s remarks “contrary to international law” and counterproductive to efforts to reduce regional tensions.
“France reiterates its commitment to the implementation of the two-state solution, with Israel and Palestine living side by side in peace and security, which is the only prospect for a just and lasting settlement of the Israeli-Palestinian conflict,” the ministry said in a statement.
Critics also pointed at Nili Kupfer-Naouri, president of the “Israel is Forever” association, who sparked outrage in 2023, after the Israel-Hamas war started, when she tweeted that “no civilian in Gaza was innocent.”
On Wednesday night, several hundred protesters marched through central Paris, denouncing the event as a “gala of hatred and shame.”
“Imagine if an association were hosting a gala for Hezbollah or Hamas — there’s no way the police would allow that,” said Melkir Saib, a 30-year-old protester. “The situation is just unfair.”
The march was largely peaceful, but some demonstrators broke windows at a McDonald’s along the route.
A separate group, including Jewish leftist organizations opposed to racism and antisemitism, gathered near the Arc de Triomphe chanting slogans against the gala and Smotrich.
French authorities defended the event, with Paris police chief Laurent Nunez stating that the gala posed “no major threat to public order.”
The protests came days after tensions flared in Paris and Amsterdam related to the conflicts in the Mideast. A massive “Free Palestine” banner was displayed during a Paris Saint-Germain Champions League match against Atletico Madrid, while violence broke out in Amsterdam last week targeting fans of an Israeli soccer club.


Catholic bishops urged to boldly share church teachings — even unpopular ones

Updated 14 November 2024
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Catholic bishops urged to boldly share church teachings — even unpopular ones

  • Bishop Robert Barron: ‘And we shouldn’t be cowed by the celebrities and so on in the culture who are preaching something that’s deeply problematic.’
BALTIMORE: Several US Catholic bishops on Wednesday encouraged the church to boldly share Vatican teachings on a range of hot-button issues, including the condemnation of abortion, euthanasia, surrogacy and gender-affirming surgery.
The prelates acknowledged theirs is often a countercultural view.
“We have been too apologetic for too long,” said Bishop Robert Barron, a media-savvy cleric who leads the Winona-Rochester diocese in Minnesota. “And we shouldn’t be cowed by the celebrities and so on in the culture who are preaching something that’s deeply problematic.”
The remarks came during the bishops’ annual fall meeting and a presentation on a Vatican declaration released in April. “Dignitas Infinita,” or “Infinite Dignity,” clarifies church teaching that promotes the dignity of all people and the protection of life from its earliest stages through death.
“The goal is to apply the lessons of ‘Dignitas Infinita’ to our American society,” said Barron, who praised the declaration for its “distinctively Catholic voice” – one that is not Democratic or Republican, liberal or conservative.
The 20 pages of “Infinite Dignity” were five years in the making and single out a range of harms, including forced migration and sexual abuse. In it, the Vatican labels gender-affirming surgery and surrogacy as violations of human dignity, comparing them to abortion and euthanasia.
Pope Francis has reached out to LGBTQ+ people throughout his papacy, and the document was a disappointing setback, if not unexpected, for transgender people and supporters of their rights. It comes during an election year in the United States where there has been a conservative backlash to transgender rights.
Bishop Thomas Daly of Spokane, Washington, spoke to the meeting about how Catholic schools can be a vehicle for educating young people about Catholic sexual ethics.
“We want our students to see the church’s teaching on sexuality as an expression of this deeper understanding of the human person, and not simply just a set of rules that stand in opposition to our popular culture,” Daly said.
Bishop Michael Burbidge of Arlington, Virginia, who is finishing a term as chair of the USCCB committee on pro-life activities, expressed gratitude to the Vatican and called the declaration “incredibly timely.”
“Sadly, many states continue to enshrine abortion in their state constitutions,” he told the gathering, referencing recent state ballot initiatives. “We know we still have so much work to do.”
“Our work is not only to change laws, but to change hearts, to change minds,” Burbidge added.
Throughout their meeting, the US bishops have reaffirmed their anti-abortion commitments, even in the face of losses at the ballot box.
Voters supported 7 out of 10 abortion rights state ballot measures this election. Even in Florida, where the abortion rights amendment failed, 57 percent of voters supported the measure, just shy of the 60 percent it needed to pass.
Archbishop Joseph Naumann of Kansas City earlier told the gathering during an evangelization discussion that the success of abortion rights ballot initiatives should be “a wake-up call for us.” He said more pointed language is needed to help people accept church teaching on life issues.
In his opening address, Archbishop Timothy Broglio, president of the US Conference of Catholic Bishops, laid out a vision of proclaiming church teaching, even when it’s not popular or convenient.
“We never back-pedal or renounce the clear teaching of the Gospel. We proclaim it in and out of season,” said Broglio. “We must insist on the dignity of the human person from womb to tomb, be unstinting in our commitment.”

US envoy says Mexico not safe, blames ex-president for failed security

Updated 14 November 2024
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US envoy says Mexico not safe, blames ex-president for failed security

  • Salazar criticizes Lopez Obrador’s security policy
  • Sheinbaum to follow Lopez Obrador’s security strategy

MEXICO CITY: The US ambassador to Mexico, Ken Salazar, said on Wednesday that the country is not safe and criticized the previous president for a failed security policy and refusing to accept American assistance.
“The reality is that at the moment Mexico is not safe,” Salazar said during a press conference at his residence in Mexico City.
The ambassador criticized former President Andres Manuel Lopez Obrador directly, saying security coordination between Mexico and the US had suffered during his term.
“Unfortunately this coordination has failed in the last year, in great part because the previous president did not want to receive help from the United States,” he said.
Lopez Obrador’s attempt to address the root causes of violence, a strategy he called “hugs not bullets,” did “not work,” Salazar said.
He added he hoped that President Claudia Sheinbaum, who took office last month, would have greater success in fighting crime and violence by investing more in security.
Sheinbaum, who belongs to the same party as Lopez Obrador, has stressed that her security policy will follow closely that of the previous president.
The comments come as relations between Lopez Obrador and Salazar have become increasingly fraught in recent months, after the ambassador criticized a judicial overhaul being driven by the former president.
It marks a distinct change from the earlier part of Lopez Obrador’s presidency when the two were regarded as having a close working relationship — a proximity that some US diplomats privately criticized.
Mexico has suffered a recent wave of violence with hundreds killed in intra-cartel warfare in the state of Sinaloa as well as massacres in other states such as Queretaro where 10 people were killed in a bar over the weekend.