Genetic clues hint at hidden virus cases in Washington state

Medics prepare to transfer a patient on a stretcher to an ambulance at the Life Care Center of Kirkland, the long-term care facility linked to the two of three confirmed coronavirus cases in the state, in Kirkland, Washington, on March 1, 2020. (REUTERS/David Ryder)
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Updated 02 March 2020
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Genetic clues hint at hidden virus cases in Washington state

  • Health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus
  • The first US case was a Washington state man who had visited China, where the virus first emerged

SEATTLE: The coronavirus may have been circulating for weeks undetected in Washington state, a preliminary finding that could mean hundreds of undiagnosed cases, researchers said Sunday after analyzing the genetic sequences of viruses from two people.
Washington state, home of the nation’s first confirmed infection, has seen eight confirmed cases, including the nation’s first death from the virus this weekend.
State and local authorities stepped up testing for the illness as the number of new cases grew nationwide, with new infections announced in California, Illinois, Rhode Island, New York and Washington state. Authorities in the Seattle area said two more people had been diagnosed with the COVID-19 virus, both men in their 60s who were in critical condition, and two health care workers in California were also diagnosed.
A man in his 50s died in Washington on Saturday, and health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus. The first US case was a Washington state man who had visited China, where the virus first emerged, but several recent cases in the US have had no known connection to travelers.
In California, two health care workers in the San Francisco Bay area who cared for an earlier coronavirus patient were diagnosed with the virus on Sunday, the Alameda and Solano counties said in a joint statement.
The health care workers are both employed at NorthBay VacaValley Hospital in Vacaville, California, and had exposure to a patient treated there before being transferred to UC Davis Medical Center in Sacramento, the statement said. That patient was the first person in the US discovered to have contracted the coronavirus with no known overseas travel.
Alameda County declared a state of emergency on Sunday following the news.
Elsewhere, authorities announced Sunday a third case in Illinois and Rhode Island and New York’s first cases as worried Americans swarmed stores to stock up on basic goods such as bottled water, canned foods and toilet paper.
The hospitalized patient in Rhode Island is a man in his 40s who had traveled to Italy in February. New York confirmed Sunday that a woman in her late 30s contracted the virus while traveling in Iran. The patient is not in serious condition. She has respiratory symptoms and has been in a controlled situation since arriving in New York, according to a statement from the governor’s office.
As the fallout continued, Vice President Mike Pence and Health and Human Services Secretary Alex Azar sought to reassure the American public that the federal government is working to make sure state and local authorities are able to test for the virus. Both said during a round of TV talk show appearances Sunday that thousands more testing kits had been distributed to state and local officials, with thousands more to come.
“They should know we have the best public health system in the world looking out for them,” Azar said, adding that additional cases will be reported and the overall risk to Americans is low.
As the cases ticked up, some Americans stocked up on basic supplies — particularly in areas with diagnosed cases — and began to take note of the impact on daily life. Stores such as Costco sold out of toilet paper, bottled water and hand sanitizer outside Portland, Oregon, where a case was announced Friday. Sports games and practices were canceled into the coming school week. Some churches said they would not offer communion because of fears of viral spread.
As Americans prepared, researchers at the Fred Hutchinson Cancer Research Center and the University of Washington on Sunday said they had evidence the virus may have been circulating in the state for up to six weeks undetected — a finding that, if true, could mean hundreds of undiagnosed cases in the area. They posted their research online, but it was not published in a scientific journal or reviewed by other scientists.
Trevor Bedford, an associate professor who announced the preliminary findings on the virus in Washington state, said on Twitter late Saturday that genetic similarities between the state’s first case on Jan. 20 and a case announced Friday indicated the newer case may have descended from the earlier one. The Jan. 20 case was the first known case in the US
“I believe we’re facing an already substantial outbreak in Washington State that was not detected until now due to narrow case definition requiring direct travel to China,” he said on Twitter.
Bedford did not immediately reply to an email requesting an interview Sunday.
Scientists not affiliated with the research said the results did not necessarily surprise them and pointed out that for many people — especially younger, healthier ones — the symptoms are not much worse than a flu or bad cold.
“We think that this has a pretty high rate of mild symptoms and can be asymptomatic. The symptoms are pretty non-specific and testing criteria has been pretty strict, so those combinations of factors means that it easily could have been circulating for a bit without us knowing,” said Justin Lessler, an associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.
Dr. Adam Lauring of University of Michigan called the findings “high quality work” from scientists who’ve done similar work with the flu virus for years.
“They show their data and they show their work,” Lauring said. “It’s more than a series of tweets” because the researchers back up what they found with data that they’ve shared online. “If there’s something wrong, someone will find it.”
Dr. Carlos del Rio of Emory University School of Medicine said the findings are from respected researchers in genomic sequencing and they make sense because of the geographic proximity of the two cases.
“This is a good time to reinforce the things we all should be doing to stop the spread of flu. Wash your hands. Don’t touch your face. If you have a cold, stay home ... It’s a good time to remind ourselves of that,” he said.
Pence, named by the president to be the point-person overseeing the government’s response, said more than 15,000 virus testing kits had been released over the weekend. And, the administration is working with a commercial provider to distribute 50,000 more, he said.
The vice president said testing was among the first issues raised by governors he’s spoken with so far. Several states have begun their own testing, including Washington state, Oregon and Illinois.
“We’re leaning into it,” Pence said.
Azar said more than 3,600 people already have been tested for coronavirus and the capability exists to test 75,000 people. He forecast a “radical expansion of that” in the coming weeks.
Pence and Azar spoke a day after President Donald Trump approved new restrictions on international travel to prevent the spread within the US of the new virus, which originated in China. There are now more than 80,000 cases worldwide and about 3,000 deaths.
Two Americans are now known to have died of the virus, one in Washington state and one in China.
The new US travel restrictions apply to Iran, although travel there by Americans already is severely limited, as well as heavily affected regions of Italy and South Korea. Trump tweeted Sunday that any travelers from those countries will be screened when they arrive in the US
The number of known coronavirus cases in the US had reached76 as of Sunday, counting people evacuated from a cruise ship and the city of Wuhan in China.
Trump said Saturday at a White House news conference that he was thinking about closing the southern border with Mexico as a precaution. Azar said Sunday that Mexico has few coronavirus cases and that it would take a dramatic change in the circumstances there to prompt serious consideration of a border shutdown.
The president, Azar said, “was trying to say everything’s on the table.”
“We will take whatever measures are appropriate and necessary to protect the American people, but we don’t forecast doing that any time soon,” he said of closing the border.
Pence noted that an infectious disease expert is joining an existing White House coronavirus task force on Monday. Last week, Pence announced the addition of Debbie Birx, a State Department ambassador-at-large and medical doctor who is the administration’s global HIV/AIDS response coordinator, to the virus panel.
Despite calls by Trump and Pence for political unity in the face of the viral threat, the issue has become mired in the partisan rancor in Washington, with both Republicans and Democrats accusing each other of mining the issue for political gain.
Trump, at a political rally last week, accused Democrats of “politicizing” the issue and said their criticism of his handling of the public health challenge was their new “hoax.”
At the White House on Saturday, Trump said he was not trying to minimize the threat from the virus.
“Again, the hoax was used in respect to Democrats and what they were saying,” he said Saturday.
Democratic presidential candidate Joe Biden, who emerged victorious Saturday night from South Carolina’s primary, criticized the administration over the availability of testing kits.
Biden also panned the administration’s decision to have political appointees Pence and Azar, neither of whom are scientists by training, appear on the Sunday shows, instead of an expert like Dr. Anthony Fauci, the National Institutes of Health infectious disease chief.
Biden claimed the administration doesn’t have testing kits. Pence and Azar said thousands of kits had been distributed.
Azar said he didn’t know what Biden was talking about when the former vice president said testing kits didn’t exist. Azar said the Centers for Disease Control and Prevention had developed a lab test for coronavirus with “historic speed.”
Pence was interviewed on CNN’s “State of the Union” and Azar commented on “Fox News Sunday,” CBS’ “Face the Nation” and ABC’s “This Week.” Biden commented on CNN.


Bangladesh opens trial of ex-PM Hasina for crimes against humanity

Updated 01 June 2025
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Bangladesh opens trial of ex-PM Hasina for crimes against humanity

  • Hearing broadcast live for first in special tribunal’s history
  • Former home minister, ex-police chief ordered to be in court for second hearing on June 16

DHAKA: Bangladeshi prosecutors on Sunday opened the trial of fugitive former Prime Minister Sheikh Hasina, who is charged with orchestrating last year’s deadly crackdown on student-led protests.

Peaceful demonstrations, triggered by the reinstatement of a quota system for the allocation of civil service positions, began in early July 2024 but two weeks later they were met with a communications blackout and a violent crackdown by security forces.

In early August, as protesters defied a nationwide curfew, Hasina resigned and fled the country, ending 15 years in power of her Awami League party-led government.

“She unleashed various law enforcement and intelligence agencies against them (the protesting students) … They slaughtered the agitating students, injured them and committed crimes against humanity,” Mohammad Tajul Islam, chief prosecutor at Bangladesh’s domestic International Crimes Tribunal, told the court in his opening speech.

He charged the 77-year-old with “incitement, aiding and abetting, involvement in the commission of the crimes of murder, attempted murder, torture and other inhumane acts as part of the widespread and systematic attacks on innocent unarmed students and the public.”

The UN’s human rights office concluded in February that between July 15 and Aug. 5, 2024, the former government and its security and intelligence apparatus, together with “violent elements” linked to the Awami League, “engaged systematically in serious human rights violations and abuses in a coordinated effort to suppress the protest movement.”

It estimated that at least 1,400 people were killed during the protests, the majority by bullets from military rifles.

ICT investigators have collected video footage, audio clips, records of helicopter and drone movements, as well as statements from victims of the crackdown as part of the probe.

They also “seized records of telephonic conversations of Sheikh Hasina, in which she repeatedly confirmed that she ordered all the state agencies to eliminate innocent civilians peacefully protesting for a fair demand, using helicopters, drones and APCs (armored personnel carriers),” Islam said.

Sunday’s hearing was broadcast live for the first in the ICT’s history.

“The court accepted the charges against Sheikh Hasina, former Home Affairs Minister Asaduzzaman Khan Kamal and former police chief Chowdhury Abdullah Al-Mamun. There are five charges against them and the court accepted all five charges. We presented the charges through live broadcast before the nation,” Islam told reporters after the hearing.

Al-Mamun is the only accused who has been detained while the ex-home minister is in hiding and Hasina remains in self-imposed exile in neighboring India.

The next hearing is scheduled to take place on June 16. The tribunal ordered all three accused to be presented before the court.

The International Crimes Tribunal was established by Hasina in 2010 to investigate crimes committed by the Pakistani army and its loyalists during Bangladesh’s independence war in 1971.

Over the years, it grew to be widely seen as the Hasina government’s tool for eliminating political rivals.


Zelensky says Ukraine will send a delegation to Istanbul for talks with Russia on Monday

Updated 01 June 2025
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Zelensky says Ukraine will send a delegation to Istanbul for talks with Russia on Monday

  • In a statement on Telegram, Zelensky said that Defense Minister Rustem Umerov will lead the Ukrainian delegation, stating "we are doing everything to protect our independence, our state and our people”

KYIV: Ukraine will send a delegation to Istanbul for a new round of direct peace talks with Russia on Monday, President Volodymyr Zelensky said, even as Russia pounded Ukraine with a missile strike that killed 12 soldiers and the biggest drone assault of the three-year war.
In a statement on Telegram, Zelensky said Sunday that Defense Minister Rustem Umerov will lead the Ukrainian delegation. “We are doing everything to protect our independence, our state and our people,” Zelensky said.
Ukrainian officials had previously called on the Kremlin to provide a promised memorandum setting out its position on ending the war before the meeting takes place. Moscow had said it would share its memorandum during the talks.
Russian strike hits an army unit
Russia launched the biggest number of drones on Ukraine since the full-scale invasion three years ago, Ukraine’s air force said Sunday. The air force said 472 drones were launched over Ukraine.
Russian forces also launched seven missiles alongside the barrage of drones, said Yuriy Ignat, head of communications for the Ukrainian air force. Earlier Sunday, Ukraine’s army said at least 12 Ukrainian service members were killed and more than 60 were injured in a Russian missile strike on an army training unit.
The strike occurred at 12:50 p.m. (0950 GMT), the statement said, emphasizing that no formations or mass gatherings of personnel were being held at the time. An investigative commission was created to uncover the circumstances around the attack that led to such a loss in personnel, the statement said.
The training unit is located to the rear of the 1,000-kilometer (620-mile) active front line, where Russian reconnaissance and strike drones are able to strike.
Ukraine’s forces suffer from manpower shortages and take extra precautions to avoid mass gatherings as the skies across the front line are saturated with Russian drones looking for targets.
“If it is established that the actions or inaction of officials led to the death or injury of servicemen, those responsible will be held strictly accountable,” the Ukrainian Ground Forces’ statement said.
Meanwhile, Ukrainian drone strikes were reported deep in Russian territory Sunday, including in the Siberian region of Irkutsk, more than 4,500 kilometers (2,800 miles) east of Moscow.
It is the first time that a Ukrainian drone has been seen in the region, local Gov. Igor Kobzeva said, stressing that it did not present a threat to civilians.
Other drone strikes were also reported in Russia’s Ryazan region and the Arctic Murmansk region. No casualties were reported.
Northern pressure
Russia’s Ministry of Defense said Sunday that it had taken control of the village of Oleksiivka in Ukraine’s northern Sumy region. Ukrainian authorities in Sumy ordered mandatory evacuations in 11 more settlements Saturday as Russian forces make steady gains in the area.
Speaking Saturday, Ukraine’s top army chief, Oleksandr Syrskyi, said that Russian forces were focusing their main offensive efforts on Pokrovsk, Toretsk and Lyman in the Donetsk region, as well as the Sumy border area.


Russia and Ukraine step up the war on eve of peace talks

Emergency medics transport a wounded passenger after a road bridge collapsed on top of a passenger train in the Bryansk region.
Updated 01 June 2025
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Russia and Ukraine step up the war on eve of peace talks

  • Ukraine attacked Russian nuclear-capable long-range bombers at a military base deep in Siberia on Sunday, a Ukrainian intelligence official said

MOSCOW/KYIV: On the eve of peace talks, Ukraine and Russia sharply ramped up the war with one of the biggest drone battles of their conflict, a Russian highway bridge blown up over a passenger train and an ambitious attack on nuclear-capable bombers deep in Siberia.
After days of uncertainty over whether or not Ukraine would even attend, President Volodymyr Zelensky said Defense Minister Rustem Umerov would sit down with Russian officials at the second round of direct peace talks in Istanbul on Monday.
The first round of the talks more than a week ago yielded the biggest prisoner exchange of the war — but no sense of any consensus on how to halt the fighting.
Amid talk of peace, though, there was much war.
At least seven people were killed and 69 injured when a highway bridge in Russia’s Bryansk region, neighboring Ukraine, was blown up over a passenger train heading to Moscow with 388 people on board. No one has yet claimed responsibility.
Ukraine attacked Russian nuclear-capable long-range bombers at a military base deep in Siberia on Sunday, a Ukrainian intelligence official said, the first such attack so far from the front lines more than 4,300 km (2,670 miles) away.
The official said the operation involved hiding explosive-laden drones inside the roofs of wooden sheds and loading them onto trucks that were driven to the perimeter of the air bases.
A total of 41 Russian warplanes were hit, the official said.

Russia acknowledges air base attacks, says fires put out 
Ukraine did not tell the Trump administration about the attack in advance, Axios reporter Barak Ravid said on X, citing an unnamed Ukrainian official.
Russia’s Defense Ministry acknowledged on the Telegram messaging app that Ukraine had launched drone strikes against Russian military airfields across five regions on Sunday.
It said the attacks repelled the assaults in all but two regions — Murmansk in the far north and Irkutsk in Siberia — where “the launch of FPV drones from an area in close proximity to airfields resulted in several aircraft catching fire.”
The fires were extinguished without casualties. Some individuals involved in the attacks had been detained, the ministry said.
Russia launched 472 drones at Ukraine overnight, Ukraine’s air force said, the highest nightly total of the war so far. Russia had also launched seven missiles, the air force said.
Russia said it had advanced deeper into the Sumy region of Ukraine, and open source pro-Ukrainian maps showed Russia took 450 square km of Ukrainian land in May, its fastest monthly advance in at least six months.
US President Donald Trump has demanded Russia and Ukraine make peace and he has threatened to walk away if they do not — potentially pushing responsibility for supporting Ukraine onto the shoulders of European powers — which have far less cash and much smaller stocks of weapons than the United States.
According to Trump envoy Keith Kellogg, the two sides will in Turkiye present their respective documents outlining their ideas for peace terms, though it is clear that after three years of intense war, Moscow and Kyiv remain far apart.
Putin ordered tens of thousands of troops to invade Ukraine in February 2022 after eight years of fighting in eastern Ukraine between Russian-backed separatists and Ukrainian troops. The United States says over 1.2 million people have been killed and injured in the war since 2022.
Trump has called Putin “crazy” and berated Zelensky in public in the Oval Office, but the US president has also said that he thinks peace is achievable and that if Putin delays then he could impose tough sanctions on Russia.
In June last year, Putin set out his opening terms for an immediate end to the war: Ukraine must drop its NATO ambitions and withdraw all of its troops from the entirety of the territory of four Ukrainian regions claimed and mostly controlled by Russia.
Ukrainian negotiators in Istanbul will present to the Russian side a proposed roadmap for reaching a lasting peace settlement, according to a copy of the document seen by Reuters.
According to the document, there will be no restrictions on Ukraine’s military strength after a peace deal is struck, no international recognition of Russian sovereignty over parts of Ukraine taken by Moscow’s forces, and reparations for Ukraine.
The document also stated that the current location of the front line will be the starting point for negotiations about territory.
Russia currently controls a little under one fifth of Ukraine, or about 113,100 square km, about the same size as the US state of Ohio. 


Russian strike kills 12 Ukrainian soldiers during training: Kyiv

Updated 01 June 2025
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Russian strike kills 12 Ukrainian soldiers during training: Kyiv

  • Kyiv did not say where the strike took place, but stressed the soldiers were not taking part in a “mass gathering” and most were in their shelters during the attack

KYIV: A Russian missile strike on a Ukrainian army training area killed at least 12 soldiers and wounded dozens more Sunday, Kyiv said, in a rare admission of its military losses.
Kyiv did not say where the strike took place, but stressed the soldiers were not taking part in a “mass gathering” and most were in their shelters during the attack.
The Ukrainian army has in recent weeks faced pressure to investigate what some see as glaring lapses in ensuring the safety of training soldiers.
Six soldiers training close to the border were killed by a Russian strike last month, in what one Ukrainian opposition politician called a “crime” by army leadership.
“Today, on June 1, the enemy launched a missile strike on the location of one of the training units of the Ukrainian army,” the Ukrainian army said in a statement.
“As of 12:50 p.m. (0950 GMT), 12 people are known to have been killed and more than 60 wounded.”
“If it is established that the deaths and injuries of the servicemen were caused by the actions or inaction of officials, those responsible will be brought to strict accountability,” it added.
Separately on Sunday, the Russian army said it had captured another village in Ukraine’s northern Sumy region, where Kyiv fears Moscow could mount a fresh ground assault.
Russia claims to have captured several settlements in the region in recent weeks, and has massed more than 50,000 soldiers on the other side of the border, according to Ukrainian President Volodymyr Zelensky.
Authorities in the region have evacuated more than 200 villages amid intensified shelling.


China’s Yunnan hit with floods, mudslides from intense rains

Updated 01 June 2025
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China’s Yunnan hit with floods, mudslides from intense rains

  • Over 600 tourists visiting rural scenic spots in the area on Saturday found themselves trapped, according to Xinhua, which reported 500 of them had been rescued by Sunday

BEIJING: Heavy rainfall triggering flash floods and mudslides have damaged roads, destroyed buildings and claimed bridges, wreaking havoc in China’s southwestern Yunnan province on a long holiday weekend.
No casualties were reported but more than 4,800 residents in Gongshan county were affected, with about one-third of them urgently relocated, state news agency Xinhua said.
Over 600 tourists visiting rural scenic spots in the area on Saturday found themselves trapped, according to Xinhua, which reported 500 of them had been rescued by Sunday.
Road access to mountainous sites popular with hikers such as Bingzhongluo town and Yubeng village in neighboring Deqin county were cut off, state broadcaster CCTV.
The Dulong river saw flood waters swell to record levels, according to historical logs from a hydrological monitoring station.
A four-story building set along the river that had been evacuated collapsed, CCTV reported, showing a video of the structure tipping backwards and disappearing into a cloud of dust.
The intense rainfall over a 12-hour period disrupted power supplies. Repair work to roads and power lines was underway, said state media.
Local authorities had issued a red alert ahead of the rainstorm on Friday night but downgraded it to a yellow alert by Saturday morning.
China uses a four-color warning system that escalates from blue, yellow, orange to red according to the level of precipitation and anticipated risks.