Genetic clues hint at hidden virus cases in Washington state

Medics prepare to transfer a patient on a stretcher to an ambulance at the Life Care Center of Kirkland, the long-term care facility linked to the two of three confirmed coronavirus cases in the state, in Kirkland, Washington, on March 1, 2020. (REUTERS/David Ryder)
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Updated 02 March 2020
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Genetic clues hint at hidden virus cases in Washington state

  • Health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus
  • The first US case was a Washington state man who had visited China, where the virus first emerged

SEATTLE: The coronavirus may have been circulating for weeks undetected in Washington state, a preliminary finding that could mean hundreds of undiagnosed cases, researchers said Sunday after analyzing the genetic sequences of viruses from two people.
Washington state, home of the nation’s first confirmed infection, has seen eight confirmed cases, including the nation’s first death from the virus this weekend.
State and local authorities stepped up testing for the illness as the number of new cases grew nationwide, with new infections announced in California, Illinois, Rhode Island, New York and Washington state. Authorities in the Seattle area said two more people had been diagnosed with the COVID-19 virus, both men in their 60s who were in critical condition, and two health care workers in California were also diagnosed.
A man in his 50s died in Washington on Saturday, and health officials said 50 more people in a nursing facility in Kirkland, Washington, are sick and being tested for the virus. The first US case was a Washington state man who had visited China, where the virus first emerged, but several recent cases in the US have had no known connection to travelers.
In California, two health care workers in the San Francisco Bay area who cared for an earlier coronavirus patient were diagnosed with the virus on Sunday, the Alameda and Solano counties said in a joint statement.
The health care workers are both employed at NorthBay VacaValley Hospital in Vacaville, California, and had exposure to a patient treated there before being transferred to UC Davis Medical Center in Sacramento, the statement said. That patient was the first person in the US discovered to have contracted the coronavirus with no known overseas travel.
Alameda County declared a state of emergency on Sunday following the news.
Elsewhere, authorities announced Sunday a third case in Illinois and Rhode Island and New York’s first cases as worried Americans swarmed stores to stock up on basic goods such as bottled water, canned foods and toilet paper.
The hospitalized patient in Rhode Island is a man in his 40s who had traveled to Italy in February. New York confirmed Sunday that a woman in her late 30s contracted the virus while traveling in Iran. The patient is not in serious condition. She has respiratory symptoms and has been in a controlled situation since arriving in New York, according to a statement from the governor’s office.
As the fallout continued, Vice President Mike Pence and Health and Human Services Secretary Alex Azar sought to reassure the American public that the federal government is working to make sure state and local authorities are able to test for the virus. Both said during a round of TV talk show appearances Sunday that thousands more testing kits had been distributed to state and local officials, with thousands more to come.
“They should know we have the best public health system in the world looking out for them,” Azar said, adding that additional cases will be reported and the overall risk to Americans is low.
As the cases ticked up, some Americans stocked up on basic supplies — particularly in areas with diagnosed cases — and began to take note of the impact on daily life. Stores such as Costco sold out of toilet paper, bottled water and hand sanitizer outside Portland, Oregon, where a case was announced Friday. Sports games and practices were canceled into the coming school week. Some churches said they would not offer communion because of fears of viral spread.
As Americans prepared, researchers at the Fred Hutchinson Cancer Research Center and the University of Washington on Sunday said they had evidence the virus may have been circulating in the state for up to six weeks undetected — a finding that, if true, could mean hundreds of undiagnosed cases in the area. They posted their research online, but it was not published in a scientific journal or reviewed by other scientists.
Trevor Bedford, an associate professor who announced the preliminary findings on the virus in Washington state, said on Twitter late Saturday that genetic similarities between the state’s first case on Jan. 20 and a case announced Friday indicated the newer case may have descended from the earlier one. The Jan. 20 case was the first known case in the US
“I believe we’re facing an already substantial outbreak in Washington State that was not detected until now due to narrow case definition requiring direct travel to China,” he said on Twitter.
Bedford did not immediately reply to an email requesting an interview Sunday.
Scientists not affiliated with the research said the results did not necessarily surprise them and pointed out that for many people — especially younger, healthier ones — the symptoms are not much worse than a flu or bad cold.
“We think that this has a pretty high rate of mild symptoms and can be asymptomatic. The symptoms are pretty non-specific and testing criteria has been pretty strict, so those combinations of factors means that it easily could have been circulating for a bit without us knowing,” said Justin Lessler, an associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.
Dr. Adam Lauring of University of Michigan called the findings “high quality work” from scientists who’ve done similar work with the flu virus for years.
“They show their data and they show their work,” Lauring said. “It’s more than a series of tweets” because the researchers back up what they found with data that they’ve shared online. “If there’s something wrong, someone will find it.”
Dr. Carlos del Rio of Emory University School of Medicine said the findings are from respected researchers in genomic sequencing and they make sense because of the geographic proximity of the two cases.
“This is a good time to reinforce the things we all should be doing to stop the spread of flu. Wash your hands. Don’t touch your face. If you have a cold, stay home ... It’s a good time to remind ourselves of that,” he said.
Pence, named by the president to be the point-person overseeing the government’s response, said more than 15,000 virus testing kits had been released over the weekend. And, the administration is working with a commercial provider to distribute 50,000 more, he said.
The vice president said testing was among the first issues raised by governors he’s spoken with so far. Several states have begun their own testing, including Washington state, Oregon and Illinois.
“We’re leaning into it,” Pence said.
Azar said more than 3,600 people already have been tested for coronavirus and the capability exists to test 75,000 people. He forecast a “radical expansion of that” in the coming weeks.
Pence and Azar spoke a day after President Donald Trump approved new restrictions on international travel to prevent the spread within the US of the new virus, which originated in China. There are now more than 80,000 cases worldwide and about 3,000 deaths.
Two Americans are now known to have died of the virus, one in Washington state and one in China.
The new US travel restrictions apply to Iran, although travel there by Americans already is severely limited, as well as heavily affected regions of Italy and South Korea. Trump tweeted Sunday that any travelers from those countries will be screened when they arrive in the US
The number of known coronavirus cases in the US had reached76 as of Sunday, counting people evacuated from a cruise ship and the city of Wuhan in China.
Trump said Saturday at a White House news conference that he was thinking about closing the southern border with Mexico as a precaution. Azar said Sunday that Mexico has few coronavirus cases and that it would take a dramatic change in the circumstances there to prompt serious consideration of a border shutdown.
The president, Azar said, “was trying to say everything’s on the table.”
“We will take whatever measures are appropriate and necessary to protect the American people, but we don’t forecast doing that any time soon,” he said of closing the border.
Pence noted that an infectious disease expert is joining an existing White House coronavirus task force on Monday. Last week, Pence announced the addition of Debbie Birx, a State Department ambassador-at-large and medical doctor who is the administration’s global HIV/AIDS response coordinator, to the virus panel.
Despite calls by Trump and Pence for political unity in the face of the viral threat, the issue has become mired in the partisan rancor in Washington, with both Republicans and Democrats accusing each other of mining the issue for political gain.
Trump, at a political rally last week, accused Democrats of “politicizing” the issue and said their criticism of his handling of the public health challenge was their new “hoax.”
At the White House on Saturday, Trump said he was not trying to minimize the threat from the virus.
“Again, the hoax was used in respect to Democrats and what they were saying,” he said Saturday.
Democratic presidential candidate Joe Biden, who emerged victorious Saturday night from South Carolina’s primary, criticized the administration over the availability of testing kits.
Biden also panned the administration’s decision to have political appointees Pence and Azar, neither of whom are scientists by training, appear on the Sunday shows, instead of an expert like Dr. Anthony Fauci, the National Institutes of Health infectious disease chief.
Biden claimed the administration doesn’t have testing kits. Pence and Azar said thousands of kits had been distributed.
Azar said he didn’t know what Biden was talking about when the former vice president said testing kits didn’t exist. Azar said the Centers for Disease Control and Prevention had developed a lab test for coronavirus with “historic speed.”
Pence was interviewed on CNN’s “State of the Union” and Azar commented on “Fox News Sunday,” CBS’ “Face the Nation” and ABC’s “This Week.” Biden commented on CNN.


Explosions as Kyiv under missile attack, says mayor

Updated 4 sec ago
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Explosions as Kyiv under missile attack, says mayor

  • Kyiv Mayor Vitali Klitschko said 3 people were injured so far, and said there was reported wreckage falling in two non-residential sites
  • Last week, a Russian missile struck a residential area in President Zelensky's home city of Kryvyi Rig, killing 18, including 9 children

KYIV, Ukraine: Kyiv Mayor Vitali Klitschko said the city was under missile attack on Sunday with explosions in the Ukrainian capital, two days after a Russian missile killed 18 people in President Volodymyr Zelensky’s hometown.
Klitschko said paramedics had been sent to two districts in Kyiv, while the Ukrainian air force said missiles had entered the northern Chernihiv region.
“Explosions in the capital. Air defense is in operation,” Klitschko said on Telegram.
“The missile attack on Kyiv continues. Stay in shelters!“
He added that three people were injured so far, and said there was reported wreckage falling in two non-residential sites.
Across Ukraine, air raid alerts were also issued for the Kherson, Mykolaiv and Odesa regions.
The attacks come at a time when US President Donald Trump is pushing for a partial ceasefire between Russia and Ukraine, more than three years into Moscow’s full-scale invasion, while seeking a thaw in ties with the Kremlin.

On Saturday, Zelensky slammed the US embassy for what he called a “weak” statement that did not blame Russia for the deadly missile strike on his home city Kryvyi Rig. Nine children were among the 18 fatalities.
In one of the deadliest strikes in recent weeks, a Russian missile struck a residential area near a children’s playground in the central Ukrainian city.
Seventy-two people were wounded, 12 of them children, Dnipropetrovsk regional governor Sergiy Lysak said after emergency operations ended overnight.
In an emotional statement on social media, Zelensky named each of the children killed in the attack, accusing the US embassy of avoiding referring to Russia as the aggressor.
“Unfortunately, the reaction of the American embassy is unpleasantly surprising: such a strong country, such a strong people — and such a weak reaction,” Zelensky wrote.
“They are even afraid to say the word ‘Russian’ when talking about the missile that killed the children.”
The Ukrainian president took aim at the US Ambassador Bridget Brink after she posted a message on X on Friday evening that said: “Horrified that tonight a ballistic missile struck near a playground and restaurant.”
Brink, who was appointed by Trump’s predecessor Joe Biden and has been ambassador since May 2022, added that “this is why the war must end.”
Zelensky wrote on Saturday: “Yes, the war must end. But in order to end it, we must not be afraid to call a spade a spade.”
“It is wrong and dangerous to keep silent about the fact that it is Russia that is killing children with ballistic missiles,” Zelensky reiterated in his evening address.
“It only incites the scum in Moscow to continue the war and further ignore diplomacy.”

The Ukrainian leader was born in the industrial city of Kryvyi Rig, which had a pre-war population of around 600,000 people.
Zelensky said the children killed by the latest attack ranged in age from a three-year-old boy, Tymofiy, to a 17-year-old teenage boy, Nikita.
Oleksandr Vilkul, the head of Kryvyi Rig’s military administration, said three days of mourning had been declared on April 7, 8 and 9.
“This is nothing less than a mass murder of civilians,” he said.
Pictures circulated by rescue services showed several bodies, one stretched out near a playground swing.
Russia’s defense ministry said it “delivered a precision strike” in the city “where commanders of formations and Western instructors were meeting.”
The General Staff of the Ukrainian army retorted that Moscow was “trying to cover up its cynical crime” and “spreading false information.” It accused Russia of “war crimes.”
Trump, who said during his re-election campaign he could end the three-year conflict within days, is pushing the two sides to agree to a ceasefire but his administration has failed to broker an accord acceptable to both.
Zelensky said the missile attack showed Russia had no interest in stopping its full-scale invasion, launched in February 2022.
The president hailed “tangible progress” after meeting British and French military chiefs in Kyiv on Friday to discuss a plan by London and Paris to send a “reassurance” force to Ukraine if and when a deal on ending the conflict is reached.
Zelensky wrote on social media that the meeting with British Chief of the Defense Staff Tony Radakin and French counterpart Thierry Burkhard agreed “the first details on how the security contingent of partners can be deployed.”
This is one of the latest efforts by European leaders to agree on a coordinated policy after Trump sidelined them and opened direct talks with the Kremlin.
 


US to revoke all South Sudan visas over failure to accept repatriation of citizens: Rubio

Updated 12 min 18 sec ago
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US to revoke all South Sudan visas over failure to accept repatriation of citizens: Rubio

  • South Sudan had failed to respect the principle that every country must accept the return of its citizens in a timely manner, Secretary of State Marco Rubio said
  • Washington “will be prepared to review these actions when South Sudan is in full cooperation,” he added

WASHINGTON: The US said on Saturday it would revoke all visas held by South Sudanese passport holders over South Sudan’s failure to accept the return of its repatriated citizens, at a time when many in Africa fear that country could return to civil war.
US President Donald Trump’s administration has taken aggressive measures to ramp up immigration enforcement, including the repatriation of people deemed to be in the US illegally.
The administration has warned that countries that do not swiftly take back their citizens will face consequences, including visa sanctions or tariffs.
South Sudan had failed to respect the principle that every country must accept the return of its citizens in a timely manner when another country, including the US, seeks to remove them, US Secretary of State Marco Rubio said in a statement.
“Effective immediately, the United States Department of State is taking actions to revoke all visas held by South Sudanese passport holders and prevent further issuance to prevent entry into the United States by South Sudanese passport holders,” Rubio said.
“We will be prepared to review these actions when South Sudan is in full cooperation,” Rubio said.
It is time for South Sudan’s transitional government to “stop taking advantage of the United States,” he said.
South Sudan’s embassy in Washington did not respond immediately to a request for comment.
African Union mediators arrived in South Sudan’s capital Juba this week for talks aimed at averting a new civil war in the country after its First Vice President Riek Machar was placed under house arrest last week.
South Sudan President Salva Kiir’s government has accused Machar, a longtime rival who led rebel forces during a 2013-18 war that killed hundreds of thousands, of trying to stir up a new rebellion.

Machar’s detention followed weeks of fighting in the northern Upper Nile state between the military and the White Army militia. Machar’s forces were allied with the White Army during the civil war but deny any current links.
The 2013-18 war was contested largely along ethnic lines, with fighters from the Dinka, the country’s largest group, lining up behind Kiir, and those from the Nuer, the second-largest group, supporting Machar.

 


Panama wants ‘respectful’ ties with US amid canal threats

Updated 06 April 2025
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Panama wants ‘respectful’ ties with US amid canal threats

  • The United States and China are the two biggest users of the Panama Canal, which handles five percent of global maritime trade, giving it vital economic and geostrategic importance

PANAMA CITY: Panama hopes to maintain a “respectful” relationship with the United States, even as President Donald Trump has repeated threats to retake the Panama Canal, Foreign Minister Javier Martinez-Acha said Saturday.
His comments came ahead of a visit next week by US Defense Secretary Pete Hegseth, a trip made more urgent against the backdrop of Trump’s threats and his allegations of Chinese interference in the canal.
“We discussed illegal migration, organized crime, drug trafficking and (other issues),” Martinez-Acha wrote on X of a call Friday with US Deputy Secretary of State Christopher Landau. “It was a cordial and constructive exchange.”
“I reiterated that all cooperation from Panama will take place under the framework of our constitution, our laws, and the Canal Neutrality Treaty,” he wrote. “Relations with the US must remain respectful, transparent and mutually beneficial.”
The US State Department said Landau had “expressed gratitude for Panama’s cooperation in halting illegal immigration and working with the United States to secure a nearly 98 percent decrease in illegal immigration through the Darien jungle,” an arduous path northward followed by many migrants.
The two officials also discussed the sale last month by the Hong Kong company CK Hutchison to giant US asset manager BlackRock of its concession in ports at either end of the Panama Canal, Martinez-Acha added.
Panama’s comptroller has been conducting an audit of Hutchison since January.
Landau “recognized Panama’s actions in curbing malign Chinese Communist Party influence,” the State Department said.
The deal was set to close on April 2 but has been held up as Chinese regulators pursue an investigation.
The United States and China are the two biggest users of the Panama Canal, which handles five percent of global maritime trade, giving it vital economic and geostrategic importance. It was inaugurated by the United States in 1914 and has been in Panamanian hands since 1999.


Tens of thousands of Spaniards march across the country to protest the growing housing crisis

Updated 06 April 2025
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Tens of thousands of Spaniards march across the country to protest the growing housing crisis

  • The housing crisis has hit particularly hard in Spain, where there is a strong tradition of home ownership and scant public housing for rent

BARCELONA, Spain: Tens of thousands of Spaniards marched in protests held across the European country on Saturday in anger over high housing costs with no relief in sight.
Government authorities said that 15,000 marched in Madrid, while organizers said 10 times that many took to the streets of the capital. In Barcelona, the city hall said 12,000 people took part in the protest, while organizers claimed over 100,000 did.
The massive demonstration of social angst that is a major concern for Spain’s left-wing government was organized by housing activists and backed by Spain’s main labor unions.
The housing crisis has hit particularly hard in Spain, where there is a strong tradition of home ownership and scant public housing for rent. Rents have been driven up by increased demand. Buying a home has become unaffordable for many, with market pressures and speculation driving up prices, especially in big cities and coastal areas.
A generation of young people say they have to stay with their parents or spend big just to share an apartment, with little chance of saving enough to one day purchase a home. High housing costs mean even those with traditionally well-paying jobs are struggling to make ends meet.
“I’m living with four people and still, I allocate 30 or 40 percent of my salary to rent,” said Mari Sánchez, a 26-year-old lawyer in Madrid. “That doesn’t allow me to save. That doesn’t allow me to do anything. It doesn’t even allow me to buy a car. That’s my current situation, and the one many young people are living through.”
Housing Minister Isabel Rodríguez said on X that “I share the demand of the numerous people who have marched today: that homes are for living in and not for speculating.”
Lack of public housing
The average rent in Spain has almost doubled in the last 10 years. The price per square meter rose from 7.2 euros ($7.90) in 2014 to 13 euros last year, according to real estate website Idealista. The increase is bigger in Madrid and Barcelona.
Incomes have failed to keep up, especially for younger people in a country with chronically high unemployment.
Spain does not have the public housing that other European nations have invested in to cushion struggling renters from a market that is pricing them out.
Spain is near the bottom end of Organization for Economic Co-operation and Development countries with public housing for rent making up under 2 percent of all available housing. The OECD average is 7 percent. In France it is is 14 percent, Britain 16 percent and the Netherlands 34 percent.
Angry renters point to instances of international hedge funds buying up properties, often with the aim of renting them to foreign tourists. The question has become so politically charged that Barcelona’s city government pledged last year to phase out all its 10,000 permits for short-term rentals, many of them advertised on platforms like Airbnb, by 2028.
Marchers in Madrid on Saturday chanted “Get Airbnb out of our neighborhoods” and held up signs against short-term rentals. In Barcelona, someone carried a sign reading “I am not leaving, vampire,” apparently in a message to would-be real estate speculator seeking to drive him out of his home.
Authorities under pressure
The central government’s biggest initiative for curbing the cost of housing is a rent cap mechanism it has offered to regional authorities, based on a price index established by the housing ministry. The government says the measure has slightly reduced rents in Barcelona, one of the few areas it has been applied.
But government measures have not proven enough to stop protests over the past two years. Experts say the situation likely won’t improve anytime soon.
“This is not the first, nor will it be the last, (housing protest) given the severity of the housing crisis,” Ignasi Martí, professor with the Esade business school and head of its Dignified Housing Observatory, said in an email.
“We saw this with the financial crisis (of 2008-2012) when (a protest movement) lasted until there was a certain economic recovery and a reduction in the social tension,” Marti added.


Protesters tee off against Trump and Musk in ‘Hands Off!’ rallies across the US

Updated 06 April 2025
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Protesters tee off against Trump and Musk in ‘Hands Off!’ rallies across the US

  • Over 1,200 “Hands Off!” demonstrations were planned by more than 150 groups
  • Trump chided for “tearing this country apart” as he goes golfing amid tariff turmoil

Opponents of President Donald Trump and billionaire Elon Musk rallied across the US on Saturday to protest the administration’s actions on government downsizing, the economy, human rights and other issues.
More than 1,200 “Hands Off!” demonstrations were planned by more than 150 groups, including civil rights organizations, labor unions, LBGTQ+ advocates, veterans and elections activists. The protest sites included the National Mall in Washington, D.C., state capitols and other locations in all 50 states.
Protesters assailed the Trump administration’s moves to fire thousands of federal workers, close Social Security Administration field offices, effectively shutter entire agencies, deport immigrants, scale back protections for transgender people and cut federal funding for health programs.
Musk, a Trump adviser who owns Tesla, SpaceX and the social media platform X, has played a key role in government downsizing as the head of the newly created Department of Government Efficiency. He says he is saving taxpayers billions of dollars.
Kelley Robinson, president of the Human Rights Campaign advocacy group, spoke at the Washington protest, criticizing the Trump administration’s treatment of the LBGTQ+ community.
“The attacks that we’re seeing, they’re not just political. They are personal, y’all,” she said. “They’re trying to ban our books, they’re slashing HIV prevention funding, they’re criminalizing our doctors, our teachers, our families and our lives. This is Donald Trump’s America and I don’t want it y’all. We don’t want this America, y’all. We want the America we deserve, where dignity, safety and freedom belong not to some of us, but to all of us.”

Thousands of people marched in New York City’s midtown Manhattan. In Massachusetts thousands more gathered on Boston Common holding signs including “Hands off our democracy,” “Hands off our Social Security” and “Diversity equity inclusion makes America strong. Hands off!”
In Ohio, hundreds rallied in the rain at the Statehouse in Columbus.
Roger Broom, 66, a retiree from Delaware County, Ohio, said at the Columbus rally that he used to be a Reagan Republican but has been turned off by Trump.
“He’s tearing this country apart,” Broom said. “It’s just an administration of grievances.”
Hundreds of people also demonstrated in Palm Beach Gardens, Florida, a few miles from Trump’s golf course in Jupiter, where he spent the morning at the club’s Senior Club Championship. People lined both sides of PGA Drive, encouraging cars to honk and chanting slogans against Trump.
Archer Moran from Port St. Lucie, Florida, said, “They need to keep their hands off of our Social Security.”
“The list of what they need to keep their hands off of is too long,” Moran said. “And it’s amazing how soon these protests are happening since he’s taken office.”
The president plans to go golfing again Sunday, according to the White House.
Asked about the protests, the White House said in a statement that “President Trump’s position is clear: he will always protect Social Security, Medicare, and Medicaid for eligible beneficiaries. Meanwhile, the Democrats’ stance is giving Social Security, Medicaid, and Medicare benefits to illegal aliens, which will bankrupt these programs and crush American seniors.”
Activists have staged nationwide demonstrations against Trump or Musk multiple times since Trump returned to office. But the opposition movement has yet to produce a mass mobilization like the Women’s March in 2017, which brought thousands of women to Washington, D.C., after Trump’s first inauguration, or the Black Lives Matter demonstrations that erupted in multiple cities after George Floyd’s killing in 2020.
In Charlotte, North Carolina, protesters said they were supporting a variety of causes, from Social Security and education to immigration and women’s reproductive rights.
“Regardless of your party, regardless of who you voted for, what’s going on today, what’s happening today is abhorrent,” said Britt Castillo, 35, of Charlotte. “It’s disgusting and as broken as our current system might be, the way that the current administration is going about trying to fix things — it is not the way to do it. They’re not listening to the people.”
“All they’re doing is making sure that they have a parachute for them and their rich friends, and everybody else here that lives here — that makes the gears turn for this country — are just screwed at the end of the day,” she said.