WASHINGTON: The US is fast-tracking antimalarial drugs for use as a treatment against the new coronavirus, President Donald Trump said Thursday, following encouraging early results in France and China.
Chloroquine and hydroxychloroquine have not been given a formal green light in the US to fight the pandemic, but the Food and Drug Administration (FDA) said it would work with domestic makers to expand production as it studied their efficacy.
The drugs are already approved for malaria, lupus and rheumatoid arthritis, and doctors in the US may prescribe any drug they believe is appropriate medically.
“We’re going to be able to make that drug available almost immediately, and that’s where the FDA has been so great,” Trump told reporters, referring to both compounds.
The US has recorded 10,755 cases of new coronavirus infection, 154 of them fatal. But authorities expect the number to increase steeply in the coming days because of increased levels of testing after initial delays.
“If there is an experimental drug that is potentially available, a doctor could ask for that drug to be used in a patient. We have criteria for that and very speedy approval for that,” said FDA Commissioner Stephen Hahn.
“As an example, many Americans have read studies and heard media reports about this drug chloroquine, which is an anti-malarial drug.
“That’s a drug that the president directed us to take a closer look at, as to whether an expanded use approach to that could be done to actually see if that benefits patients.”
Chloroquine and hydroxychloroquine are synthetic forms of quinine, which is found in the barks of cinchona trees of Latin America and has been used to treat malaria for centuries.
Some in the wider scientific community have cautioned more research is needed to prove that they really work and are safe for COVID-19.
But French drug maker Sanofi said on Wednesday it was ready to offer the French government millions of doses of hydroxychloroquine, sold under its brand name Plaquenil, in light of a “promising” study carried out by scientist Didier Raoult of the IHU Mediterranee Infection in Marseille.
Raoult reported this week that after treating 24 patients for six days with Plaquenil, the virus had disappeared in all but a quarter of them.
The research has not yet been peer reviewed or published, and Raoult had come under fire by some scientists and officials in his native France for potentially raising false hopes.
“I’m just doing my duty, and I am happy to see that now eight or nine countries recommend chloroquine treatment for patients with this new coronavirus,” he told AFP.
Several clinical trials are also underway in China, where authorities have announced positive results but not yet published their data.
Karine Le Roch, a professor of cell biology at the University of California, Riverside told AFP she was encouraged by recent work in France and China.
“I will say there is a very small number of patients, but if the results are correct, it seems to indeed decrease the viral loads of infected patients,” she said.
“It’s encouraging but we have to make sure the results are accurate and then confirm that with a larger number of patients.”
Scientists understand how these alkaloid compounds work at the cellular level to fight malaria parasites — but it’s not yet known how they are fighting the coronavirus, Le Roch added.
“It’s highly possible that this compound is changing the acidity of the cells infected with the virus,” she told AFP.
“And then the enzymes that are needed for the virus to replicate cannot work as efficiently as they would work without the drug.”
But not everyone is convinced.
Writing in the journal Antiviral Research, French scientists Franck Touret and Xavierde de Lamballerie urged caution, noting that chloroquine had been proposed several times for the treatment of acute viral diseases in humans without success, including HIV.
They added that finding the right dose was crucial because “chloroquine poisoning has been associated with cardiovascular disorders that can be life-threatening.”
US fast-tracking antimalarials to treat coronavirus
https://arab.news/5a3c9
US fast-tracking antimalarials to treat coronavirus
- Some in the wider scientific community have cautioned more research is needed to prove that they really work and are safe for COVID-19
Muslims who voted for Trump upset by his pro-Israel cabinet picks
Hassan Abdel Salam, a former professor at the University of Minnesota said Trump’s staffing plans were not surprising, but had proven even more extreme that he had feared
WASHINGTON: US Muslim leaders who supported Republican Donald Trump to protest against the Biden administration’s support for Israel’s war on Gaza and attacks on Lebanon have been deeply disappointed by his Cabinet picks, they tell Reuters.
“Trump won because of us and we’re not happy with his Secretary of State pick and others,” said Rabiul Chowdhury, a Philadelphia investor who chaired the Abandon Harris campaign in Pennsylvania and co-founded Muslims for Trump.
Muslim support for Trump helped him win Michigan and may have factored into other swing state wins, strategists believe.
Trump picked Republican senator Marco Rubio, a staunch supporter of Israel for Secretary of State. Rubio said earlier this year he would not call for a ceasefire in Gaza, and that he believed Israel should destroy “every element” of Hamas. “These people are vicious animals,” he added.
Trump also nominated Mike Huckabee, a former Arkansas governor and staunch pro-Israel conservative who backs Israeli occupation of the West Bank and has called a two state solution in Palestine “unworkable,” as the next ambassador to Israel.
He has picked Republican Representative Elize Stefanik, who called the UN a “cesspool of antisemitism” for its condemnation of deaths in Gaza, to serve as US ambassador to the United Nations.
Rexhinaldo Nazarko, executive director of the American Muslim Engagement and Empowerment Network (AMEEN), said Muslim voters had hoped Trump would choose Cabinet officials who work toward peace, and there was no sign of that.
“We are very disappointed,” he said. “It seems like this administration has been packed entirely with neoconservatives and extremely pro-Israel, pro-war people, which is a failure on the on the side of President Trump, to the pro-peace and anti-war movement.”
Nazarko said the community would continue pressing to make its voices heard after rallying votes to help Trump win. “At least we’re on the map.”
Hassan Abdel Salam, a former professor at the University of Minnesota, Twin Cities and co-founder of the Abandon Harris campaign, which endorsed Green Party candidate Jill Stein, said Trump’s staffing plans were not surprising, but had proven even more extreme that he had feared.
“It’s like he’s going on Zionist overdrive,” he said. “We were always extremely skeptical...Obviously we’re still waiting to see where the administration will go, but it does look like our community has been played.”
The Trump campaign did not immediately respond to an email seeking comment.
Several Muslim and Arab supporters of Trump said they hoped Richard Grenell, Trump’s former acting director of national intelligence, would play a key role after he led months of outreach to Muslim and Arab American communities, and was even introduced as a potential next secretary of state at events.
Another key Trump ally, Massad Boulos, the Lebanese father-in-law of Trump’s daughter Tiffany, met repeatedly with Arab American and Muslim leaders.
Both promised Arab American and Muslim voters that Trump was a candidate for peace who would act swiftly to end the wars in the Middle East and beyond. Neither was immediately reachable.
Trump made several visits to cities with large Arab American and Muslim populations, include a stop in Dearborn, a majority Arab city, where he said he loved Muslims, and Pittsburgh, where he called Muslims for Trump “a beautiful movement. They want peace. They want stability.”
Rola Makki, the Lebanese American, Muslim vice chair for outreach of the Michigan Republican Party, shrugged off the criticism.
“I don’t think everyone’s going to be happy with every appointment Trump makes, but the outcome is what matters,” she said. “I do know that Trump wants peace, and what people need to realize is that there’s 50,000 dead Palestinians and 3,000 dead Lebanese, and that’s happened during the current administration.”
Trump promises to end wars with a ‘strong military’
- “We’re going to work on the Middle East and we’re going to work very hard on Russia and Ukraine. It’s got to stop,” Trump added
PALM BEACH, United States: US President-elect Donald Trump on Thursday promised a “strong military,” as he repeated his pledge to end the war between Russia and Ukraine.
Trump, who campaigned on an “America First” foreign policy, has said previously that he wanted to strike a deal between Kyiv and Moscow, without giving details, and end bloodshed in the Middle East.
“We have to get back to a great country with low taxes and a strong military. We’re going to fix our military, we did once and now we’re going to have to do it again,” he said Thursday at a gala organized by the America First Policy Institute at his Mar-a-Lago resort in Palm Beach, Florida.
“We’re going to work on the Middle East and we’re going to work very hard on Russia and Ukraine. It’s got to stop,” Trump added.
He also criticized the “big chunk” of US spending on Afghanistan, from where American troops withdrew in 2021 after two decades of fighting an insurgency by the Taliban, which returned to power that year.
Trump’s re-election has the potential to upend the almost three-year conflict between Russia and Ukraine, throwing into question Washington’s multibillion-dollar support for Kyiv, which is crucial to its defense.
The Republican said on the campaign trail that he could end the fighting within hours and has indicated he would talk directly with Russian President Vladimir Putin.
Trump has not said how he intends to strike a peace deal on Ukraine or what terms he would propose.
Germany’s Scholz urges Putin in phone call to open talks with Ukraine
- Scholz also demanded the withdrawal of Russian troops from Ukraine and reaffirmed Germany’s continued support for Ukraine
- “The Chancellor urged Russia to show willingness to enter talks with Ukraine with the aim of achieving a just and lasting peace,” the spokesperson said
BERLIN: German Chancellor Olaf Scholz urged Russian President Vladimir Putin in a rare phone call on Friday to begin talks with Ukraine that would open the way for a “just and lasting peace.”
In a one-hour phone conversation, their first in almost two years, Scholz also demanded the withdrawal of Russian troops from Ukraine and reaffirmed Germany’s continued support for Ukraine, a German government spokesman said.
The call comes as Ukraine faces increasingly difficult conditions on the battlefield amid shortages of arms and personnel while Russian forces make steady advances.
“The Chancellor urged Russia to show willingness to enter talks with Ukraine with the aim of achieving a just and lasting peace,” the spokesperson said in a statement.
“He stressed Germany’s unbroken determination to back Ukraine in its defense against Russian aggression for as long as necessary,” the spokesperson added.
Scholz spoke with Ukraine’s President Volodymyr Zelensky ahead of his call with Putin and would brief the Ukrainian leader on the outcome afterwards, the spokesperson said.
Germany is Ukraine’s largest financial backer and its largest provider of weapons after the United States, whose future support for Kyiv appears uncertain following Donald Trump’s victory in the US presidential election.
Trump has repeatedly criticized the scale of Western financial and military aid to Ukraine and has suggested he can put a swift end to the war, without explaining how.
Scholz and Putin last spoke in December 2022, 10 months after Russia launched its full-scale invasion of Ukraine, plunging relations with the West into their deepest freeze since the Cold War.
Scholz, the most unpopular German chancellor on record, is preparing for a national election on Feb. 23 in which his Social Democrats face stiff competition from left-wing and far-right parties that are critical of Germany’s backing for Ukraine.
Croatian health minister arrested and sacked over alleged graft
- Beros’ lawyer Laura Valkovic told local media that he denied any criminal responsibility
- The prime minister’s comments came after Croatia’s Office for the Suppression of Corruption and Organized Crime (USKOK) said it was conducting several arrests
SARAJEVO: Croatian Health Minister Vili Beros was sacked on Friday after being arrested on suspicion of corruption, Prime Minister Andrej Plenkovic said.
Beros’ lawyer Laura Valkovic told local media that he denied any criminal responsibility. The health ministry declined to comment.
The prime minister’s comments came after Croatia’s Office for the Suppression of Corruption and Organized Crime (USKOK) said it was conducting several arrests.
The European Public Prosecutor’s Office also said it had initiated an investigation against eight people, including Beros and the directors of two hospitals in Zagreb, over alleged bribery, abuse of authority and money laundering.
Croatia’s State Attorney Ivan Turudic, whose office works closely with USKOK, said there were two parallel investigations into the alleged crimes and that EPPO has not informed his office nor USKOK about its investigation.
Turudic said Beros was accused of trade of influence. He said two other individuals had been arrested and one legal entity would be investigated on suspicion of the criminal act of receiving a bribe.
The people detained will be brought before an investigative judge who will decide on any pre-trial detention, Turudic told a news conference.
The EPPO said that a criminal group seeking to secure financing for the sale of medical robotic devices in several hospitals was suspected of giving bribes to officials to try to win contracts for projects, including EU funded ones.
“What is obvious is that this is about criminal acts of corruption,” Plenkovic said. “On behalf of the government, I want to say that agencies authorized for criminal persecution should investigate everything.”
Protesters storm parliament in breakaway Georgian region Abkhazia over deal with Russia
- Eshsou Kakalia, an opposition leader and former deputy prosecutor general, said the parliament building was under the control of the protesters
- “We will now seek the resignation of the current president of Abkhazia,” he was quoted by Russia’s Interfax news agency as saying
TBILISI: Protesters stormed the parliament of the Russian-backed breakaway Georgian region of Abkhazia on Friday and opposition politicians demanded the resignation of the self-styled president over an unpopular investment agreement with Moscow.
Protesters used a truck to smash through the metal gates surrounding the parliament in the capital Sukhumi. Video from the scene then showed people climbing through windows after prying off metal bars and chanting in the corridors.
Eshsou Kakalia, an opposition leader and former deputy prosecutor general, said the parliament building was under the control of the protesters.
“We will now seek the resignation of the current president of Abkhazia,” he was quoted by Russia’s Interfax news agency as saying. Protesters also broke into the presidential administration offices located in the same building as the parliament.
Emergency services said at least eight people were taken to hospital.
The presidential administration said in a statement that authorities were preparing to withdraw the investment agreement with Russia that some Abkhaz fear will price them out of the property market.
Russia recognized Abkhazia and another breakaway region, South Ossetia, as independent states in 2008 after Russian troops repelled a Georgian attempt to retake South Ossetia in a five-day war.
Most of the world recognizes Abkhazia as part of Georgia, from which it broke away during wars in the early 1990s, but Russian money has poured into the lush sub-tropical territory where Soviet-era spa resorts cling to the Black Sea coast.
RUSSIAN MONEY
Abkhazian lawmakers had been set to vote on Friday on the ratification of an investment agreement signed in October in Moscow by Russian Economy Minister Maxim Reshetnikov and his Abkhazian counterpart, Kristina Ozgan.
Abkhazian opposition leaders say the agreement with Moscow, which would allow for investment projects by Russian legal entities, would price locals out of the property market by allowing far more Russian money to flow in.
The opposition said in a statement that the protesters’ actions were not against Russian-Abkhazian relations.
“Abkhazian society had only one demand: to protect the interests of our citizens and our business, but neither the president nor the parliament have heard the voice of the people until today,” Interfax cited the statement as saying.
Earlier this week Abkhazia’s self-styled president, Aslan Bzhania, held an emergency security council meeting after protesters blocked a key highway and rallied in central Sukhumi to demand the release of four activists.
The activists, who were subsequently freed, had been detained for opposing the passage of a law regulating the construction industry which references the Russian-Abkhazian agreement.
In 2014, demonstrators stormed the presidential headquarters, forcing then-leader Alexander Ankvab to flee. He later resigned over accusations of corruption and misrule.
Opposition leader Raul Khadzhimba, elected following the unrest in 2014, was himself forced to step down in 2020 after street protests over disputed election results.
