LONDON: A manufacturer of a possible COVID-19 vaccine being developed by British scientists said on Friday it may know by the end of May if it can make a million doses a month with a view to building stocks for commercial supply when the vaccine is approved.
Cobra Biologics is one of the firms working to make a potential vaccine known as ChAdOx1 nCoV-19 being developed by scientists at the University of Oxford.
Chief Executive Peter Coleman said the firm is not responsible for proving the efficacy of the vaccine, with those trials being run by the Oxford team, and there was a lot of risk involved in the project.
But he said that if a 200-liter manufacturing run planned for the middle of May were successful, the company would be ready to produce 1 million doses a month.
“(That’s) more than enough for clinical trials, but also potentially a start to stock up for commercial supply,” Coleman told Reuters, adding that it could have capacity for up to two million doses in repeat batches.
“The speed at which we’re operating is much quicker than it ordinarily is. And to start building up batches for commercial supply before you’ve even got to phase one (clinical trials) is pretty unusual.”
British pharmaceutical firm AstraZeneca has joined the Oxford vaccine program to develop, produce and distribute the potential vaccine to help make it available as soon as possible if it succeeds in clinical trials.
Coleman said AstraZeneca’s involvement could help with the rapid scaling-up of the vaccine on a global stage, but said that Cobra Biologics and two other contract development and manufacturing organizations (CDMOs) with a similar capacity that were already involved would still play a pivotal role.
“The current consortium of CDMOs will be a fundamental part of the manufacturing of this vaccine. AstraZeneca has a lot of capability,” he said.
“But I think at this moment in time, given the intensity and speed that’s required, it makes common sense to stick with the CDMOs you’ve got at the moment and then at some point in the future, transition to something else.”
Coleman said that processes that might previously have taken years were being boiled down to five months, and that safety work already carried out on a Middle East respiratory syndrome (MERS) vaccine could help speed up the development of a COVID-19 vaccine.
“It’s not from a standing start. There’s been a lot of work, and the products have been modified in such a way that the safety work from the early clinical trials is equally applicable,” Coleman said.
Asked about comments by AstraZeneca CEO Pascal Soriot that it will know whether the vaccine will be effective in June or July, Coleman said that his firm was focused on the manufacture of the vaccine rather than determining its efficacy.
“I trust the university with that July outcome,” he said. “And then if it’s positive, the race is on to produce as many batches as possible.”
Potential UK coronavirus vaccine producer eyes making a million doses a month
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Potential UK coronavirus vaccine producer eyes making a million doses a month
- Cobra Biologics is one of the firms working to make a potential vaccine known as ChAdOx1 nCoV-19
- British pharmaceutical firm AstraZeneca has also joined the Oxford vaccine program
Ethiopians celebrate Christmas as natural calamities and conflict take their toll
- The patriarch of the Ethiopian Orthodox Church called for reconciliation and peace in a nation where conflict has been often fueled by ethnic strife
ADDIS ABABA: Ethiopia’s Orthodox Christians are celebrating Christmas with prayers for peace in the Horn of Africa nation that has faced persistent conflict in recent years.
Ethiopians follow the Julian calendar, which runs 13 days later than the Gregorian calendar, used by Catholic and Protestant churches. They traditionally celebrate by slaughtering animals and joining family members to break the fast after midnight.
The patriarch of the Ethiopian Orthodox Church, Abune Mathias, in his televised Christmas Eve message called for reconciliation and peace in a nation where conflict has been often fueled by ethnic strife. Different parts of Ethiopia recently have also faced natural calamities, including mudslides. Earthquakes last week in the remote regions of Afar, Amhara and Oromia have displaced thousands.
Despite the signing of a peace agreement to end the armed conflict in the northern region of Tigray in 2022, recurring conflicts in Amhara, Oromia and elsewhere have caused widespread suffering and forced 9 million children to drop out of school, according to UNICEF.
Almaz Zewdie, who was among thousands of Orthodox Christians attending ceremonies in Addis Ababa’s Medhanyalem Church, said she was praying for peace.
She was draped in an all-white traditional attire to mark the end of a 43-day fasting period and the birth of Jesus Christ.
“I lost friends and my livelihood,” said Zewdie, a merchant from the tourist town of Gondar, speaking of the toll of the conflict in Amhara, where government troops have been fighting members of a local militia.
Isaias Seyoum, a priest in Addis Ababa’s Selassie Church, said the celebration of Christmas is more than just feasting and merrymaking. It is also a time to share meals with needy people and help those impacted by conflict, including many sheltering in Addis Ababa, he said.
Baroness Warsi accuses UK Conservative Party of demonizing her over Islamophobia claims
- Party recently told Warsi she would not have whip restored in UK’s upper house of parliament
- Internal inquiry clears Warsi of ‘bringing the party into disrepute’ over support for pro-Palestinian protester
LONDON: The UK’s first Muslim cabinet member has accused her Conservative Party of attempting to “demonize” her after she criticized the party over Islamophobia.
Baroness Sayeeda Warsi was told recently she was not welcome back into the Conservative Party in the UK’s upper house of parliament, where she holds a seat, The Independent reported on Wednesday.
Warsi resigned from the party in the House of Lords in September, claiming the Conservatives had moved too far to the right.
The former co-chair of the Conservative Party had also come under pressure from senior party members over language used in a tweet supporting a pro-Palestinian protester.
Warsi has now been cleared of being “divisive” and “bringing the party into disrepute” by a disciplinary panel investigating the tweet.
But the Conservatives wrote to Warsi saying that while she could remain a member of the party, they would not restore to her the party whip, meaning she could not be affiliated with the party in the Lords.
In response, Warsi said she had not asked to have the whip restored, and accused the Conservatives of playing games.
She told The Independent that the party was attempting to “demonize” her for challenging the party’s “rising levels of extremism, racism and Islamophobia.”
Warsi was appointed as the first Muslim Conservative Party chair in 2010 by Prime Minister David Cameron as he sought to modernize the party.
But in recent years the Conservatives have shifted further right as they seek to counter the growing popularity of far-right parties.
In March, Warsi said the party had become known as “the institutionally xenophobic and racist party.” She has also repeatedly accused it of failing to tackle Islamophobia within the party and criticized significant figures for their rhetoric over immigration.
In 2014, she resigned as a minister in the Foreign and Commonwealth Office over the government’s “morally indefensible” approach to Gaza.
Warsi’s decision to resign the whip in September was, she said: “A reflection of how far right my party has moved and the hypocrisy and double standards in its treatment of different communities.”
The move came after complaints against her for a tweet congratulating a pro-Palestinian protester acquitted of a racially aggravated public order offense. The protester had used a placard depicting Rishi Sunak, who was prime minister at the time, as a coconut.
Poland shuts consulate in Saint Petersburg on Russian order
- Russia ordered the closure in December after Poland said in October it was closing Russia’s consulate in the Polish city of Poznan
- “The Polish Consulate General in Saint Petersburg was shut down upon Russia’s withdrawal of its consent to the activity of the Polish post,” Poland’s foreign ministry said
WARSAW: Poland announced Wednesday it had shut its consulate in the Russian city of Saint Petersburg, after Russia ordered the closure in a tit-for-tat move.
Russia ordered the closure in December after Poland said in October it was closing Russia’s consulate in the Polish city of Poznan, accusing Moscow of “sabotage” attempts in the country and its allies.
“The Polish Consulate General in Saint Petersburg was shut down upon Russia’s withdrawal of its consent to the activity of the Polish post,” Poland’s foreign ministry said in a statement Wednesday.
“It is in retaliation for a decision of the Polish foreign minister to close down Russia’s Consulate General in Poznan in the aftermath of acts of sabotage committed on Polish territory and linked to Russian authorities.”
After Russia ordered the closure, Poland responded that it would close all the Russian consulates on its soil if “terrorism” it blamed on Moscow carried on.
Tensions between Russia and NATO member Poland have escalated since Moscow sent troops into Ukraine in February 2022, with both sides expelling dozens of diplomats.
Poland is a staunch ally of Kyiv and has been a key transit point for Western arms heading to the embattled country since the conflict began.
In one of the largest espionage trials, Poland in 2023 convicted 14 citizens of Russia, Belarus and Ukraine of preparing sabotage on behalf of Moscow as part of a spy ring.
They were found guilty of preparing to derail trains carrying aid to Ukraine, and monitoring military facilities and critical infrastructure in the country.
2 Russian firefighters died in blaze caused by Ukraine drone: governor
- “As a result of the liquidation (of the fire), there are two dead,” said the governor of Saratov region
MOSCOW: Two Russian firefighters died on Wednesday fighting a blaze caused by a Ukrainian drone attack, the local governor said, after Kyiv said it hit an oil depot that supplies Russia’s air force.
“Unfortunately, as a result of the liquidation (of the fire), there are two dead — employees of the emergency situations ministry’s fire department,” Roman Busagrin, governor of the Saratov region where the strike happened, said on Telegram.
UK police investigating suspicious vehicle in central London, carry out controlled explosions
- Road closures are in place in the vicinity of Regent Street and New Burlington Street in central London, police said on X
LONDON: British police carried out a number of controlled explosions as a precaution in central London as they investigated a suspicious vehicle on Wednesday, the city’s police force said on social media.
Road closures are in place in the vicinity of Regent Street and New Burlington Street in central London, police said on X.
