LONDON: British officials authorized a COVID-19 vaccine for emergency use on Wednesday, greenlighting the world’s first shot against the virus that’s backed by rigorous science and taking a major step toward eventually ending the pandemic.
The go-ahead for the vaccine developed by American drugmaker Pfizer and Germany's BioNTech comes as the virus surges again in the United States and Europe, putting pressure on hospitals and morgues in some places and forcing new rounds of restrictions that have devastated economies.
The Medicines and Healthcare Products Regulatory Agency, which licenses drugs in the UK, recommended the vaccine could be used after it reviewed the results of clinical trials that showed the vaccine was 95% effective overall — and that it also offered significant protection for older people, among those most at risk of dying from the disease. But the vaccine remains experimental while final testing is done.
“Help is on its way,'' British Health Secretary Matt Hancock told the BBC, adding that the situation would start to improve in the spring.
“We now have a vaccine. We're the first country in the world to have one formally clinically authorized but, between now and then, we've got to hold on, we've got to hold our resolve," he said.
Other countries aren’t far behind: Regulators in the United States and the European Union also are vetting the Pfizer shot along with a similar vaccine made by competitor Moderna Inc. British regulators also are considering another shot made by AstraZeneca and Oxford University.
Hancock said Britain expects to begin receiving the first shipment of 800,000 doses “within days,'' and people will begin receiving shots as soon as the National Health Service gets the vaccine.
Doses everywhere are scarce, and initial supplies will be rationed until more is manufactured in the first several months of next year.
A government committee will release details of vaccination priorities later Wednesday, but Hancock said nursing home residents, people over 80, and healthcare workers and other care workers will be the first to receive the shot.
Pfizer said it would immediately begin shipping limited supplies to the UK — and has been gearing up for even wider distribution if given a similar nod by the U.S. Food and Drug Administration, a decision expected as early as next week.
Pfizer CEO Albert Bourla called the UK decision “a historic moment.”
“We are focusing on moving with the same level of urgency to safely supply a high-quality vaccine around the world,” Bourla said in a statement.
While the UK has ordered 40 million doses of the Pfizer vaccine, enough for 20 million people, it’s not clear how many will arrive by year’s end. Hancock said the UK expects to receive “millions of doses" by the end of this year, adding that the actual number will depend on how fast Pfizer can produce the vaccine.
One concern about the Pfizer-BioNTech vaccine is that it must be stored and shipped at ultra-cold temperatures of around minus 70 degrees Celsius (minus 94 degrees Fahrenheit), adding to the challenge of distributing the vaccine around the world.
Pfizer says it has developed shipping containers that use dry ice to keep the vaccine cool. GPS-enabled sensors will allow the company to track each shipment and ensure they stay cold, the company says.
“Pfizer has vast experience and expertise in cold-chain shipping and has an established infrastructure to supply the vaccine worldwide, including distribution hubs that can store vaccine doses for up to six months," the company said in a statement.
The company also says it has agreed to work with other vaccine makers to ensure there is sufficient supply and a range of vaccines, “including those suitable for global access.”
Every country has different rules for determining when an experimental vaccine is safe and effective enough to use. Intense political pressure to be the first to roll out a rigorously scientifically tested shot colored the race in the US and Britain, even as researchers pledged to cut no corners. In contrast, China and Russia have offered different vaccinations to their citizens ahead of late-stage testing.
The shots made by US-based Pfizer and its German partner BioNTech were tested in tens of thousands of people. And while that study isn’t complete, early results suggest the vaccine is 95% effective at preventing mild to severe COVID-19 disease. The companies told regulators that of the first 170 infections detected in study volunteers, only eight were among people who’d received the actual vaccine and the rest had gotten a dummy shot.
“This is an extraordinarily strong protection,” Dr. Ugur Sahin, BioNTech’s CEO, recently told The Associated Press.
The companies also reported no serious side effects, although vaccine recipients may experience temporary pain and flu-like reactions immediately after injections.
Final testing must still be completed. Still to be determined is whether the Pfizer-BioNTech shots protect against people spreading the coronavirus without showing symptoms. Another question is how long protection lasts.
The vaccine also has been tested in only a small number of children, none younger than 12, and there’s no information on its effects in pregnant women.
UK authorizes Pfizer coronavirus vaccine for emergency use
https://arab.news/z875a
UK authorizes Pfizer coronavirus vaccine for emergency use
- The vaccine remains experimental while final testing is done
- Hancock said Britain expects to begin receiving the first shipment of 800,000 doses “within days,'' and people will begin receiving shots as soon as the NHS gets the vaccine
G20 leaders gather for deadlocked talks on climate, Middle East, Ukraine wars
- Wars which have bitterly divided G20 members are set to feature prominently in discussions in Brazil
- Biden will attend his last summit of world’s leading economies with China’s XI as the most influential leader
Rio de Janeiro: G20 leaders began arriving for a summit in Brazil on Monday to try reignite deadlocked climate talks and overcome their differences on the Middle East and Ukraine wars ahead of Donald Trump’s return to the White House.
US President Joe Biden will attend his last summit of the world’s leading economies, but as a lame duck leader eclipsed by Chinese President Xi Jinping, the most influential leader at this year’s meeting.
Brazil’s left-wing President Luiz Inacio Lula da Silva is using his hosting duties to promote issues close to his heart, including fighting hunger and climate change and taxing the super-rich.
But the wars which have bitterly divided G20 members are also set to feature prominently in the discussions.
A Brazilian foreign ministry source said Monday that some countries wanted to renegotiate a draft summit communique.
“For Brazil and other countries the text is already finalized, but some countries want to open up some points on wars and climate,” he told AFP.
Biden’s decision Sunday to allow Ukraine to use long-range US missiles to strike targets inside Russia — a major policy shift — could prompt European allies to also review their stance.
G20 leaders are also under pressure to try rescue UN climate talks in Azerbaijan, which have stalled on the issue of greater climate finance for developing countries.
UN Secretary-General Antonio Guterres has called for G20 members, who account for 80 percent of global emissions, to show “leadership” to facilitate a deal.
Security is tight for the gathering, which comes days after a failed bomb attack on Brazil’s Supreme Court in Brasilia by a suspected far-right extremist, who killed himself in the process.
The get-together will cap a farewell diplomatic tour by Biden which took him to Lima for a meeting of Asia-Pacific trading partners, and then to the Amazon in the first such visit for a sitting US president.
Biden, who has looked to burnish his legacy as time runs down on his presidency, insisted in the Amazon that his climate record would survive another Trump mandate.
All eyes at the stalled COP29 climate conference in Azerbaijan are on Rio to break an impasse over how to raise $1 trillion a year for developing countries to cope with global warming.
Rich countries want fast-developing economies like China and Gulf states to also put their hands in their pockets.
The meeting comes in a year marked by another grim litany of extreme weather events, including Brazil’s worst wildfire season in over a decade, fueled by a record drought blamed at least partly on climate change.
At the last G20 in India, leaders called for a tripling of renewable energy sources by the end of the decade, but without explicitly calling for an end to the use of fossil fuels.
Conspicuously absent from the summit is Russian President Vladimir Putin, whose arrest is sought by the International Criminal Court over the Ukraine war.
Lula, 79, told Brazil’s GloboNews channel on Sunday that he did not want the wars in Ukraine and the Middle East to take the focus off global poverty.
“Because if not, we will not discuss other things which are more important for people that are not at war, who are poor people and invisible to the world,” he said.
The summit opens on Monday with Lula, a former steelworker who grew up in poverty, launching a “Global Alliance against Hunger and Poverty.”
Brazil is also pushing for higher taxes on billionaires.
Lula had faced resistance to parts of his agenda from Argentinian President Javier Milei, a libertarian Trump uber-fan who met the Republican last week at his Mar-a-Lago resort.
The head of the Argentine delegation, Federico Pinedo, told AFP that Buenos Aires has raised some objections and would not “necessarily” sign the text, however. He did not elaborate.
But the Brazilian foreign ministry source on Monday downplayed the likelihood of Argentina blocking a consensus.
Why has ethnic violence escalated in India’s Manipur state again?
- On May 3, 2023, members of the Kuki and Naga tribes launched protest against extension of benefits to dominant Meiteis
- Latest violence flared this month after 31-year-old woman from Kuki tribe was found burned to death in a village in Jiribam district
Hundreds of people defied a curfew to stage demonstrations in India’s northeastern state of Manipur over the weekend and 23 were arrested for violence as tensions between two ethnic communities flared up again.
These are the reasons behind the violence in the border state.
HOW DID THE MANIPUR VIOLENCE BEGIN?
On May 3, 2023, members of the Kuki and Naga tribes, who inhabit Manipur’s hills and are regarded as Scheduled Tribes, or India’s most disadvantaged groups, launched a protest against the possible extension of their benefits to the dominant Meiteis.
The Meitei have sought special benefits for more than a decade, but received a fillip in April last year after the Manipur High Court recommended the state government should consider the demand and set a deadline of mid-May.
Meiteis account for half of Manipur’s population and extending limited affirmative action quotas to them would mean they would get a share of education and government jobs reserved for Kukis and Nagas.
Meiteis have traditionally lived in Manipur’s more prosperous valley region that makes up 10 percent of the state’s area.
They have also had better access to employment and economic opportunities. Nagas and Kukis live in the poorly developed hill regions.
The imbalance in development that has favored the valley over the hills has been a point of contention and rivalry between the ethnic groups.
WHAT WERE THE TRIGGERS?
The groups co-existed peacefully until unrelated events in 2023 exposed old faultlines.
Manipur shares a nearly 400-km (250-mile) border with Myanmar and the coup there in 2021 pushed thousands of refugees into the Indian state.
Kukis share ethnic lineage with Myanmar’s Chin tribe and Meiteis feared they would be outnumbered by the arrival of the refugees.
WHY IS PEACE YET TO RETURN?
Both the Meiteis and Kukis are known to be flush with arms, including automatic weapons either stolen from the state police or sourced from Myanmar.
The Indian Army and federal paramilitary forces in the state cannot act independently and are legally bound to work with state police and authorities, who analysts say are also divided along ethnic lines.
Kukis also accuse Biren Singh, the chief minister of the Bharatiya Janata Party-ruled state and a Meitei, of complicity in violence against them and have sought his removal. Singh denies the accusations.
WHAT IS BEHIND THE LATEST SPIRAL OF VIOLENCE?
The latest violence flared this month after a 31-year-old Kuki woman was found burned to death in a village in Jiribam district, an area that was untouched by the conflict until June.
Kuki groups blamed Meitei militants for the act.
Kukis and Meiteis have moved to separate parts elsewhere in Manipur since the clashes last year but Jiribam still has a mixed population, leading to tensions and violence.
Days after the incident, 10 armed Kuki men were killed in a gunfight with security forces after they tried to attack a police station in Jiribam district, and security forces retaliated. During this gunfight, a Meitei family of six people went missing.
On Friday, bodies of three of the six were found floating in a river, triggering angry protests in the state capital Imphal. Police said on Sunday they had arrested 23 people for ransacking and setting fire to the homes of lawmakers and ministers, in a second straight day of unrest in the area.
Emergency declared as smog in New Delhi hits highest level this year
- New Delhi was the world’s most polluted city on Monday, according to IQAir
- PM 2.5 concentration was 138.4 times higher than WHO’s recommended levels
NEW DELHI: New Delhi was in a medical emergency on Monday as toxic smog engulfing the Indian capital reached the highest level this year, prompting authorities to close schools and urge people to stay indoors.
Pollution in Delhi and the surrounding metropolitan area — home to around 55 million people — reached the “severe plus” category as some areas reached an Air Quality Index score of 484, this year’s highest, according to the Central Pollution Control Board.
On the AQI scale from 0 to 500, good air quality is represented by levels below 50, while levels above 300 are dangerous.
Delhi was ranked as the most polluted city in the world on Monday by Swiss group IQAir, with a concentration of PM 2.5, 138.4 times higher than the World Health Organization’s recommended levels.
“All of North India has been plunged into a medical emergency,” Delhi Chief Minister Atishi Marlena Singh said in a press conference, adding that many cities were “reeling under severe levels of pollution.”
She said farm fires, where stubble left after harvesting rice is burnt to clear fields, were causing the extreme levels of pollution.
“Why is the (central government) not taking action against these states and implementing concrete steps? People are unable to breathe. I am getting calls from people complaining about breathing and respiratory issues,” she said.
“All of North India is paying the price for this, especially children and elderly who are struggling to breathe.”
Authorities in Delhi have directed all schools to move classes online and tightened restrictions on construction activities and vehicle movements.
Mahesh Palawat, vice president of meteorology and climate change at forecast company Skymet Weather, said people in the capital region are faced with serious health risks.
“If they are non-smokers, then they will also inhale at least 30 to 40 cigarettes per day (at these pollution levels). So, you can imagine how bad it is for our health,” he told Arab News.
“PM 2.5 is a very minute particle (that can be inhaled). It is so minute that it can go into our blood vessels also, so it is very harmful and leads to various diseases, particularly for older people and infants who have breathing problems.”
Palawat is expecting the air quality to remain at this level for at least a few more days.
“It will remain in the very poor to serious category in coming days also,” he said.
Emergency declared in New Delhi as smog hits highest level this year
- New Delhi was the world’s most polluted city on Monday, according to IQAir
- PM 2.5 concentration was 138.4 times higher than WHO’s recommended levels
New Delhi: New Delhi was in a state of ‘medical emergency’ on Monday as toxic smog engulfing the Indian capital reached the highest levels this year, prompting authorities to close schools and urge people to stay indoors.
Pollution in Delhi and the surrounding metropolitan area — home to around 55 million people — reached the “severe plus” category as some areas reached an Air Quality Index score of 484, this year’s highest, according to the Central Pollution Control Board.
On the AQI scale from 0 to 500, good air quality is represented by levels below 50, while levels above 300 are dangerous.
Delhi was ranked as the most polluted city in the world on Monday by Swiss group IQAir, with a concentration of PM 2.5, 138.4 times higher than the World Health Organization’s recommended levels.
“All of North India has been plunged into a medical emergency,” Delhi Chief Minister Atishi Marlena Singh said in a press conference, adding that many cities were “reeling under severe levels of pollution.”
She said farm fires, where stubble left after harvesting rice is burnt to clear fields, were causing extreme levels of pollution.
“Why is the (central government) not taking action against these states and implementing concrete steps? People are unable to breathe. I am getting calls from people complaining about breathing and respiratory issues,” she said.
“All of North India is paying the price for this, especially children and elderly who are struggling to breathe.”
Authorities in Delhi have directed all schools to move classes online and tightened restrictions on construction activities and vehicle movements.
Mahesh Palawat, vice president of meteorology and climate change at forecast company Skymet Weather, said people in the capital region are faced with serious health risks.
“If they are non-smokers, then they will also inhale at least 30 to 40 cigarettes per day (at these pollution levels). So, you can imagine how bad it is for our health,” he told Arab News.
“PM 2.5 is a very minute particle (that can be inhaled). It is so minute that it can go into our blood vessels also, so it is very harmful and leads to various diseases, particularly for older people and infants who have breathing problems.”
Palawat is expecting the air quality to remain at this level for at least a few more days.
“It will remain in the very poor to serious category in coming days also,” he said.
Palestinian NGO to ask UK court to block F-35 parts to Israel over Gaza war
- West Bank-based Al-Haq is taking legal action against Britain’s Department for Business and Trade at London’s High Court
LONDON: Britain is allowing parts for F-35 fighter jets to be exported to Israel despite accepting they could be used in breach of international humanitarian law in Gaza, lawyers for a Palestinian rights group told a London court on Monday.
West Bank-based Al-Haq, which documents alleged rights violations by Israel and the Palestinian Authority, is taking legal action against Britain’s Department for Business and Trade at London’s High Court.
Israel has been accused of violations of international humanitarian law in the Gaza war, with the UN Human Rights Office saying nearly 70 percent of fatalities it has verified were women and children, a report Israel rejected.
Israel says it takes care to avoid harming civilians and denies committing abuses and war crimes in the conflicts with Hamas in Gaza and Hezbollah in Lebanon.
Al-Haq’s case comes after Britain in September suspended 30 of 350 arms export licenses, though it exempted the indirect export of F-35 parts, citing the impact on the global F-35 program.
Al-Haq argues that decision was unlawful as there is a clear risk F-35s could be used in breach of international humanitarian law.
British government lawyers said in documents for Monday’s hearing that ministers assessed Israel had committed possible breaches of international humanitarian law (IHL) in relation to humanitarian access and the treatment of detainees.
Britain also “accepts that there is clear risk that F-35 components might be used to commit or facilitate a serious violation of IHL,” its lawyer James Eadie said.
Eadie added that Britain had nonetheless decided that F-35 components should still be exported, quoting from advice to defense minister John Healey that suspending F-35 parts “would have a profound impact on international peace and security.”
A full hearing of Al-Haq’s legal challenge is likely to be heard early in 2025.
The Hamas-run Gaza health ministry says more than 43,800 people have been confirmed killed since the war erupted on Oct. 7, 2023.
Hamas militants killed around 1,200 people in attacks on communities in southern Israel that day, and hold dozens of some 250 hostages they took back to Gaza, according to Israeli tallies.
