The announcement comes as a result of continued demand for Emirates' service between Dubai and Glasgow, which began in 2004.
The additional flight, coupled with an aircraft upgrade on the existing service, will increase Emirates' capacity to Glasgow by 47 percent, an extra 199 seats each way per day.
It will also provide an additional 13 tons of daily cargo capacity.
"This announcement illustrates our commitment to Scotland and to our wider UK route network in difficult economic times," said Salem Obaidalla, Emirates' senior vice president, commercial operations, Europe and Russian Federation.
"Our Glasgow route has been a real success story, and we are confident that there is demand for additional services flying to and from Dubai and beyond to our global network of over 100 destinations. The introduction of a First Class cabin on both daily flights also means greater choice for passengers, while increased cargo capacity means more export business opportunities for cargo shippers in Scotland," added Obaidalla.
"From a starting point in 2004, Emirates' Dubai route has proved a huge success, generating over AED931 million to date for the local economy and bringing more than 687,000 inbound passengers to Glasgow," said councillor Gordon Matheson, leader of Glasgow City Council and Chair of Glasgow City Marketing Bureau, who joined an announcement event in Glasgow.
The Glasgow authorities estimate that the twice-daily service will deliver a local economic benefit of AED187 million with almost 140,000 inbound passengers in 2012 alone.
"As part of our strategy to support economic growth, the Scottish government is determined to improve our international air connections," said Scotland's Deputy First Minister Nicola Sturgeon.