UAE’s Mubadala Healthcare contributes to UK COVID-19 diabetes drug trial

The Arcadia trial began on Sept. 29 and involved hospitalized patients with mild to moderate COVID-19 symptoms. (File/Reuters)
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Updated 09 November 2020
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UAE’s Mubadala Healthcare contributes to UK COVID-19 diabetes drug trial

  • The trial, known as Arcadia, was approved following preclinical research
  • If successful, it could be prescribed by doctors for people with diabetes

DUBAI: A leading UAE health care provider revealed that it was contributing to a British-based drug trial that will help patients with diabetes overcome the effects of the coronavirus disease (COVID-19).
Mubadala Healthcare is part-funding the trial of an immune-dampening drug approved by the UK’s Medicines and Healthcare products Regulatory Agency.
The trial, known as Arcadia, was approved following preclinical research that suggested a specific enzyme “could help diabetes patients with COVID-19 by dampening the overactive response of the immune system that is typically acute in those patients with raised blood glucose levels,” Mubadala Healthcare said in a statement.
The trial began on Sept. 29 and involved hospitalized patients with mild to moderate COVID-19 symptoms.

“There are more than 1 million people living with diabetes in our country, and this group is identified as being particularly vulnerable to effects of the COVID-19,” said Abdulla Abdul Aziz Al-Shamsi, head of Mubadala Healthcare.
He added that the investment was one of many being made by Mubadala Healthcare “to enable the UAE government and population to mitigate the effects of the disease, and provide the resources needed to support local and international efforts that will lead to solutions for this pandemic.”
The company is contributing to the research grant along with Excalibur Medicines Ltd. (EML), several private partners, and the UK government.
The compound itself was originally developed by Anglo-Swedish pharmaceuticals group, AstraZeneca, for another purpose but research conducted by biomedical research charity St. George Street Capital Ltd. (SGS) found that it had the potential to help people with diabetes.
EML founder, Sir Chris Evans, said: “The funding from Mubadala Healthcare and our other partners will allow us to fast-track this research.” He added that they “foresee a significant impact on the level of fatalities in the future.
“Treatments such as this could be vital as we are likely to be living with this virus for some time to come.”
David Tapolczay, CEO of SGS, said: “Given the current crisis, we have paused all our current research program to focus totally on this clinical trial and evaluate this potentially life-saving new drug.”
If the trial is successful, the compound could eventually be prescribed by doctors and physicians for people with diabetes who show early symptoms of COVID-19.

 


UN experts slam Israel’s blatant assault on health rights in Gaza

Updated 04 January 2025
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UN experts slam Israel’s blatant assault on health rights in Gaza

  • Reiterating charges that Israel is committing genocide in Gaza, two independent UN rights experts said they were “horrified” by the raid last Friday on Kamal Adwan, northern Gaza’s last functioning major hospital
  • UN special rapporteurs are independent experts appointed by the UN Human Rights Council but do not speak on behalf of the world body

GENEVA: UN experts have denounced Israel’s raid on an embattled hospital in northern Gaza, demanding an end to the “blatant assault” on health rights in the besieged Palestinian territory.
Reiterating charges that Israel is committing genocide in Gaza, two independent UN rights experts said they were “horrified” by the raid last Friday on Kamal Adwan, northern Gaza’s last functioning major hospital.
“For well over a year into the genocide, Israel’s blatant assault on the right to health in Gaza and the rest of the occupied Palestinian territory is plumbing new depths of impunity,” the experts said.
The joint statement was from Francesca Albanese, the independent UN special rapporteur on the rights situation in the Palestinian territories, and Tlaleng Mofokeng, the special rapporteur on the right to health.

FASTFACT

The joint statement was from Francesca Albanese, the independent UN special rapporteur on the rights situation in the Palestinian territories, and Tlaleng Mofokeng, the special rapporteur on the right to health.

Israel’s diplomatic mission in Geneva dismissed the statement as “far removed from the truth,” saying it “completely ignores critical facts and the broader context of Hamas’s exploitation of civilian infrastructure for military purposes.”
The Israeli military has repeatedly accused Hamas of using hospitals as command centers, something Hamas denies.
The military “undertook every effort to protect civilians,” the Israeli mission said, insisting its “actions highlight Israel’s commitment to international law and the protection of civilian infrastructure, even under the most challenging circumstances.”
Israel’s military said it had killed more than 20 suspected militants and detained more than 240, including the hospital’s director, Hossam Abu Safiyeh, describing him as a suspected Hamas militant.
In their statement, Albanese and Mofokeng said they were “gravely concerned” at Safiyeh’s detention and demanded his “immediate release.”
“Yet another doctor to be harassed, kidnapped, and arbitrarily detained by the occupation forces,” they said.
“This is part of a pattern by Israel to continuously bombard, destroy, and fully annihilate the realization of the right to health in Gaza.”
UN special rapporteurs are independent experts appointed by the UN Human Rights Council but do not speak on behalf of the world body.
The experts also highlighted “disturbing reports” that Israeli forces had allegedly carried out extrajudicial executions of some people near the hospitals, including a Palestinian man reportedly holding a white flag.
They pointed to figures provided by the Health Ministry in Gaza indicating that at least 1,057 Palestinian health and medical professionals have been killed since the war erupted following the Palestinian group’s Oct. 7, 2023 attack inside Israel.
The World Health Organization has repeatedly denounced the high number of attacks on health care staff and facilities in the war: 1,273 attacks on health care in Gaza and the West Bank have been recorded since the start of the war.
WHO chief Tedros Adhanom Ghebreyesus warned on X that the pace of desperately needed medical evacuations out of Gaza was “excruciatingly slow.”
“Only 5,383 patients have been evacuated with support from WHO since October 2023, of which only 436 since the Rafah crossing was closed” last May, he said.
He said more than 12,000 people were awaiting medical evacuation from Gaza.
“At this rate, it would take 5-10 years to evacuate all these critically ill patients, including thousands of children,” he added.
“In the meantime, their conditions get worse and some die.”

 


Lebanon’s PM discusses with Syria’s de facto ruler relations between two countries

Updated 29 min 14 sec ago
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Lebanon’s PM discusses with Syria’s de facto ruler relations between two countries

Lebanon’s caretaker prime minister, Najib Mikati, in a phone call on Friday with Syria’s de facto ruler Ahmed Al-Sharaa, discussed relations between the two countries, according to a statement from Mikati’s office posted on X, and said that he received an invitation from Sharaa to visit Syria to discuss common files.
Sharaa also affirmed that Syrian authorities took the necessary measures to restore calm on the border between the two countries, the post on X said.


Syrian foreign minister to visit Qatar, UAE and Jordan

Updated 04 January 2025
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Syrian foreign minister to visit Qatar, UAE and Jordan

DAMASCUS: The top diplomat in Syria’s new leadership said Friday he will make official visits to Qatar, the UAE and Jordan this week, having just been in Saudi Arabia on his first trip in office.
The new government is eager for foreign investment to help rebuild the country’s infrastructure and boost the economy, shattered by more than a decade of war.
“This week, I will represent my country, Syria, on an official visit to our brothers in Qatar, the United Arab Emirates, and the Hashemite Kingdom of Jordan,” its foreign minister Asaad Al-Shibani said in a statement on X.
“We look forward to these visits contributing to support stability, security, economic recovery, and building distinguished partnerships,” he added.
Earlier this week, Shaibani headed a high-ranking delegation to Riyadh that included the new government’s defense minister and intelligence chief.
It was the first foreign visit by Syria’s new rulers since they ousted president Bashar Assad last month.


Lebanese army unit clashes with Syrian gunmen at illegal border crossing

Updated 03 January 2025
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Lebanese army unit clashes with Syrian gunmen at illegal border crossing

  • Interior minister defends additional security measures at airport and land crossing points

BEIRUT: A Lebanese army unit clashed with a group of armed Syrian nationals at the border on Friday as the soldiers attempted to “close an illegal crossing” in the Maarboun-Baalbek area of eastern Lebanon.

The Syrians were trying to forcibly reopen the crossing with a bulldozer, the army said. Soldiers fired warning shots into the air and Syrians responded by returning fire.

The “armed Syrians fired at the Lebanese soldiers, injuring one and sparking a clash between both sides,” the army command added. “Artillery shells were used” and other Lebanese army units in the area also responded with strict military measures, it added.

Subsequently, “reinforcements from the army’s mobile regiment arrived in the area, following the retreat of the armed Syrians, some of whom sustained injuries,” and the illegal crossing remained closed.

Maarboun is a town in Baalbek-Hermel governorate, and a natural crossing point between the two countries. However it is an illegal crossing mainly used by smugglers and human traffickers. The surrounding area is known to be pro-Hezbollah.

The incident at the illegal crossing coincided with the actions of Syrian authorities on Friday morning that prevented hundreds of Lebanese from crossing the border between Masnaa in Lebanon and Jdeidet Yabous in Syria.

The Syrians suddenly imposed new conditions on Lebanese visitors, including requirements that they have a hotel reservation and at least $2,000 in cash. People visiting Syria for surgery or other medical care must now have proof of an appointment and a Syrian sponsor who can confirm their identity. A valid residence permit for the stay in Syria is also required. Lebanese authorities imposed similar rules on Syrians entering Lebanon after the civil war in Syria began more than a decade ago.

Buses carrying Lebanese passengers who intended to visit Syria were forced turn back at the border as a result of the new Syrian rules.

Lebanon’s General Security Directorate decided to “prohibit any Lebanese from entering Syria through illegal crossings between both countries in Bekaa and the north, pending clarity during this stage,” a source from the agency said.

After the fall of President Bashar Assad and his regime in Syria in early December, the directorate held two meetings with officials from the new Syrian administration to discuss the regulation of movement between the two countries.

Though media delegations, politicians and civilians have crossed into Syria in recent days, Lebanese authorities have tightened security at land crossings, following similar actions at Rafic Hariri International Airport in Beirut.

Normal operations at the airport resumed on Friday after an incident on Thursday night involving an aircraft belonging to Iranian airline Mahan Air. Airport security decided to conduct a thorough inspection of all passengers when the plane landed, including luggage belonging to diplomats on board. The diplomats protested and chose instead to leave their luggage at the airport. It was taken to a storage facility for inspection the following day using scanners.

Footage circulated on social media apparently showing young men on motorcycles heading to the airport to protest against the measures. It was believed the heightened security was motivated by concerns that passengers might be carrying money for delivery to Hezbollah. A second Iranian plane that landed on Friday faced similar security measures.

Lebanon’s interior minister, Bassam Mawlawi, described the move as a routine procedure and added: “What the airport security is doing aims to protect Lebanon and the Lebanese people. We are enforcing the law, protecting the airport and safeguarding all of Lebanon because it cannot withstand any new aggression.”

The decision covered the inspection of all luggage, he said, including that carried by diplomats.

The heightened measures drew criticism from the vice president of the Supreme Islamic Shiite Council, Sheikh Ali Al-Khatib. During his Friday sermon, he called on the interior minister “to demonstrate his heroism against the enemy, not against those who made sacrifices to defend Lebanon’s sovereignty.”

Also on Friday, US Maj. Gen. Jasper Jeffers, head of the international committee monitoring the implementation of the ceasefire agreement between the Israeli army and Hezbollah, toured Khiam, where the Lebanese army was deployed after the withdrawal of the Israeli forces. He was accompanied by Brig. Gen. Tony Faris, commander of the Lebanese army’s 7th Brigade.

Their visit came as Israel continued to face criticism for violating Lebanese sovereignty, including reconnaissance flights over southern Lebanon, extending as far as the southern suburbs of Beirut. Israeli forces were also accused of demolishing houses and roads in Dhayra and Jebbayn, and there were renewed warnings to residents of southern Lebanon not to return to homes in border areas until further notice.

There was a heavy presence of UN Interim Force in Lebanon forces along the Bayada-Naqoura road. The Lebanese army has placed concrete barriers on the road to Naqoura, preventing people other than UNIFIL personnel from entering. The UN force’s headquarters is located there.

The Lebanese army said it was surveying military remnants in Naqoura following the withdrawal of Israeli forces from the town on Thursday. When this task is complete, Lebanese forces will be redeployed to the area, it added.


Hamas wants Gaza ceasefire deal as soon as possible, senior official says

Updated 03 January 2025
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Hamas wants Gaza ceasefire deal as soon as possible, senior official says

  • Mediators Qatar, Egypt and the US have been engaged in months of back-and-forth talks between Israel and Hamas

CAIRO: Hamas said a new round of indirect talks on a Gaza ceasefire resumed in Qatar’s Doha on Friday, stressing the group’s seriousness in seeking to reach a deal as soon as possible, senior Hamas official Basem Naim said.

The new talks will focus on agreeing on a permanent ceasefire and the withdrawal of Israeli forces, he added. 

Mediators Qatar, Egypt and the US have been engaged in months of back-and-forth talks between Israel and Hamas that have failed to end more than a year of devastating conflict in Gaza.

A key obstacle to a deal has been Israel’s reluctance to agree to a lasting ceasefire.

On Thursday, Prime Minister Benjamin Netanyahu’s office said he had authorized Israeli negotiators to continue talks in Doha.

In December, Qatar expressed optimism that “momentum” was returning to the talks following Donald Trump’s election victory in the United States.

But a war of words then broke out with Hamas accusing Israel of setting “new conditions” while Israel accused Hamas of creating “new obstacles” to a deal.

In its Friday statement, Hamas said it reaffirmed its “seriousness, positivity and commitment to reaching an agreement as soon as possible that meets the aspirations and goals of our steadfast and resilient people.